Triple primary malignancy (synchronous papillary and follicular thyroid carcinomas and diffuse B-Cell lymphoma of the submandibular Gland and Cervical Lymph Nodes) in a 70-Year-old woman.
- Author:
Ar John Paul M. ROXAS
1
Author Information
- Publication Type:Case Report
- MeSH: Human; Female; Aged: 65-79 Yrs Old; Carcinoma; B-lymphocytes; Adenocarcinoma, Follicular; Neoplasms; Submandibular Gland; Lymph Nodes; Lymphoma, B-cell; Thyroid Gland; Thyroid Cancer, Papillary; Thyroidectomy
- From: Philippine Journal of Otolaryngology Head and Neck Surgery 2025;40(Supplement):36-40
- CountryPhilippines
-
Abstract:
OBJECTIVES
To report a case of triple primary malignant neoplasms in a 70-year-old woman diagnosed with follicular and papillary thyroid carcinoma and diffuse B-cell lymphoma of the right submandibular gland and cervical lymph nodes.
METHODSDesign:Case Report
Setting:Tertiary Government Training Hospital
Patient: One
RESULTSA 70- year-old woman presented with a four-year history of gradually enlarging anterior neck mass, associated with a right submandibular mass and neck nodes for one year. The gradual progression of her symptoms made the patient think that it was a benign condition. This led to a delay in medical consultation. The patient underwent total thyroidectomy with functional neck dissection of the ipsilateral right neck. Histopathology revealed simultaneous follicular and papillary thyroid carcinoma, and diffuse B-cell lymphoma of the cervical lymph nodes. The patient was referred to medical oncology and nuclear medicine for further management.
CONCLUSIONOur patient was incidentally diagnosed with follicular and papillary thyroid carcinoma and diffuse B cell lymphoma of the cervical lymph nodes after surgery. Such triple primary malignant neoplasms in a single individual are rare, and as in our case, may only be diagnosed in hindsight.
