Studies on glycosides from the n-butanol fraction of Aconitum tanguticum
10.11665/j.issn.1000-5048.2026012803
- VernacularTitle:甘青乌头正丁醇部位苷类化学成分研究
- Author:
Mengyuan ZHAO
1
;
Siyang FANG
;
anting LI
;
Qien LI
;
Ke PAN
;
Zhiqi YIN
Author Information
1. 中国药科大学中药学院, 南京 211198;青海大学藏医药研究中心, 西宁 810016
- Publication Type:Journal Article 期刊文章
- Keywords:
Aconitum tanguticum;
chemical constituents;
glycosides;
isolation and identification
- From:
Journal of China Pharmaceutical University
2026;57(2):189-195
- CountryChina
- Language:Chinese
-
Abstract:
In order to investigate the chemical constituents of glycosides in Aconitum tanguticum (Maxim.) Stapf, column chromatographic techniques such as silica gel, ODS, Sephadex LH-20, and semi-preparative high performance liquid chromatography were used to afford eight glycosides from the n-butanol fraction of the 85% ethanol extract of Aconitum tanguticum. Based on the physicochemical properties and spectral data, these compounds were identified as N-4-O-(β-D-glucopyranosyl)-phenethylbenzamide (1), N-(2'-β-D-glucopyranosyl-5'-methoxysalicyl)-4-hydroxy-3-methoxyanthranilic acid methyl ester (2), N-(2'-β-D-glucopyranosyl-5'-hydroxysalicyl)-4-hydroxy-3-methoxyanthranilic acid methyl ester (3), salidroside (4), benzyl primeveroside (5), phenethanol-β-D-xylose-(1''→6')-β-D-glucopyranoside (6), 4-dihydroxyphenethoxy-8-O-β-D-[6-O-(4-O-β-D-glucopyranosyl)-feruloyl]-glucopyranoside (7), phenethanol-α-L-arabinopyranosyl-(1''→6')-β-D-glucopyranoside (8). Among them, compounds 1 and 2 were new compounds, and compounds 5,6,8 were isolated from Aconitum tanguticum for the first time.
