Factors Affecting Survival of 4892 Patients with Colorectal Cancer in Yunnan Province
10.3971/j.issn.1000-8578.2026.25.0751
- VernacularTitle:云南省4892例结直肠癌患者生存的影响因素分析
- Author:
Ruiqi CAI
1
;
Zhijian YANG
1
;
Yanyan YANG
1
;
Guoyu MA
1
;
Yuying PANG
2
;
Mengjiao ZHANG
3
;
Lei LUO
4
;
Sile LI
1
;
Min ZHAO
1
Author Information
1. Office of Cancer Prevention and Treatment, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming 650118, China.
2. Infection Control Department, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming 650118, China.
3. Outpatient Department, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming 650118, China.
4. Medical Affairs Department, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming 650118, China.
- Publication Type:CLINICALRESEARCH
- Keywords:
Colorectal cancer;
Survival analysis;
Prognostic factors;
Retrospective study
- From:
Cancer Research on Prevention and Treatment
2026;53(4):274-280
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze survival outcomes and influencing factors among patients with colorectal cancer in Yunnan Province. Methods Clinical data were retrospectively collected from 4 892 patients with colorectal cancer. Survival data were obtained through follow-up. Overall survival (OS) was calculated by using the Kaplan-Meier method. Univariate analysis was performed by applying the log-rank test. Meanwhile, multivariate analysis employed the Cox proportional hazards regression model. Results The 1-, 3-, 5-, and 10-year OS rates for the entire cohort were 91.90%, 74.40%, 64.40%, and 28.70%, respectively. Univariate analysis revealed that age, ethnicity, region, differentiation grade, TNM stage, clinical stage, metastatic status, histological type, and treatment modality (chemotherapy, radiotherapy, and surgery) were associated with patient prognosis (all P<0.05). Multivariate analysis identified age (HR=1.250), region (HR=1.262), differentiation grade (HR=0.761), clinical stage (HR=3.128), and treatment modality (chemotherapy, HR=0.644; radiotherapy, HR=1.605; surgery, HR=0.384) as independent factors affecting survival prognosis in patients with colorectal cancer (all P<0.001). Conclusion Age, region, clinical stage, and treatment modality are independent factors influencing survival among patients with colorectal cancer in Yunnan Province. In clinical practice, these factors should be integrated to develop individualized prevention and treatment strategies, thereby improving patient outcomes.
