Analysis on Characteristics and Prescriptions of Chinese Patent Medicines for Functional Diarrhea on Market
10.13422/j.cnki.syfjx.20260132
- VernacularTitle:已上市治疗功能性腹泻中成药品种特点及处方分析
- Author:
Shuangfei DENG
1
;
Siyu LI
2
;
Changyue SONG
2
;
Caiyu LIU
2
;
Daiyue DING
2
;
Xiaohui SU
2
;
Xiaoqin LUO
2
;
Haiyu ZHAO
2
;
Xiangying KONG
1
Author Information
1. Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of EducationZunyi Medical University,Zunyi 563003,China
2. Institute of Chinese materia Medicine,China Academy of Chinese Medical Sciences, Beijing 100700,China
- Publication Type:Journal Article
- Keywords:
functional diarrhea;
Chinese patent medicine;
data mining;
prescription analysis;
children's medicines
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2026;32(11):261-268
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveThis study focused on the marketed Chinese patent medicines for the treatment of Functional Diarrhea (FDr) in China and their prescription characteristics, in order to provide support for the clinical application and research and development of anti-FDr Chinese patent medicines. MethodsCollect the information of Chinese patent medicines that have been marketed to treat FDr, use Microsoft Excel 2021 software to conduct preliminary data collation and statistical analysis, and use the ancient and modern medical record cloud platform (V2.3.9) to analyze the standardized Chinese patent medicine prescriptions from the aspects of drug nature and taste, medication characteristics and prescription rules. Results147 kinds of FDr Chinese patent medicines were included in this study. There are a total of 40 varieties of FDr Chinese patent medicines suitable for children; The distribution of dosage forms is mainly pills, tablets, and capsules. 110 prescriptions were screened, among which the proportion of Chinese patent medicines for the treatment of spleen deficiency syndrome was the highest; The top three drug use frequency were licorice, Atractylodes macrocephala, and Poria cocos; The medicinal properties are mainly warm and flat, and the medicinal taste is mostly pungent, sweet and bitter, and most of them belong to the two meridians of the spleen and stomach; The association rules analysis obtains 20 strong association pairing sets; Three drug combinations were obtained by cluster analysis. ConclusionFDr Chinese patent medicine shows unique value in clinical application, especially in the field of children. However, there are still problems such as strong professionalism in the indication expression of drug instructions, limited coverage of the medical insurance catalog, and lack of high-level evidence-based medicine and pharmacoeconomic evidence. To this end, in the future, efforts should be made to build a multi-level evidence-based evidence system, improve medication compliance, and deepen research on syndrome-based medication laws, so as to enhance the clinical application value and scientific connotation of FDr Chinese patent medicines.