Application Characteristics and Patterns of Marketed Traditional Chinese Patent Medicines for Treating Abortion
10.13422/j.cnki.syfjx.20260438
- VernacularTitle:已上市治疗流产中成药应用特征与规律研究
- Author:
Changyue SONG
1
;
Shuangfei DENG
1
;
Siyu LI
1
;
Daiyue DING
1
;
Jinghong XIE
2
;
Xiaohui SU
1
;
Xiangying KONG
1
Author Information
1. Institute of Chinese Materia Medica， China Academy of Chinese Medical Science， Beijing 100700，China
2. Xiyuan Hospital， China Academy of Chinese Medical Science， Beijing 100091，China
- Publication Type:Journal Article
- Keywords:
abortion;
traditional Chinese patent medicine;
data mining;
prescription analysis
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2026;32(11):244-251
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveThis paper aims to analyze the variety characteristics and prescription patterns of marketed traditional Chinese patent medicines for treating abortion and provide references for new medicine development and clinical application. MethodsRelevant information of traditional Chinese patent medicines for treating abortion was systematically retrieved and collected. Microsoft Excel 2021 software was used to sort and statistically analyze the medicine syndrome types， quantity， market situation， and status of package inserts. Based on the Ancient and Modern Medical Case Cloud Platform （V2.3.9）， the medicine properties， flavors， meridian tropism， and medication characteristics of standardized prescriptions were analyzed. ResultsA total of 39 marketed traditional Chinese patent medicines for treating abortion in China were included. According to disease type， these medicines were categorized as therapeutic medicines for threatened abortion and recurrent spontaneous abortion. According to clinical function， they were categorized into three groups： fetus stabilization， blood nourishment， and adjunctive conditioning. They were also categorized into pre-pregnancy conditioning and post-pregnancy fetal maintenance by clinical intervention stage. Post-marketing research showed that only three products had undergone safety evaluations and one involved pharmacoeconomic research， indicating a general lack of standardized evidence-based data. Dosage forms were mainly pills and granules. Package insert analysis revealed that 15 products listed "contraindications"， while 28 included "precautions". Based on prescription inclusion and exclusion criteria， 25 products were selected for further analysis. Their therapeutic effects were mainly concentrated on "tonifying the kidney and spleen， replenishing Qi， and nourishing blood"， with core medicines including Paeoniae Radix Alba， Angelicae Sinensis Radix， and Atractylodis Macrocephalae Rhizoma. Most medicines were warm or neutral in nature， predominantly sweet and pungent in flavor， and mainly entered the spleen， liver， and kidney meridians. ConclusionTraditional Chinese patent medicines for treating abortion demonstrate clear clinical value. However， shortcomings remain， including insufficient post-marketing research， prescription homogeneity， and incomplete package inserts. Future efforts should establish a clinically value-oriented modern development pathway， strengthen safety surveillance and evidence evaluation， improve package inserts， and promote precision use to further enhance clinical value.
