Clinical Experience for Sentinel Lymphadenectomy Alone in Early Breast Cancer.
10.4048/jkbcs.2003.6.4.263
- Author:
Hy De LEE
1
;
Jin Wook CHOI
;
Do Yil KIM
;
Byeong Woo PARK
;
Il Kyun LEE
;
Hyung Jung SONG
;
Woo Hee JUNG
;
Hee Jung KIM
;
Yong Hoon RYU
;
Ki Keun OH
Author Information
1. Department of General Surgery, Yonsei University College of Medicine, Seoul, Korea. hdlee@yumc.yonsei.ac.kr
- Publication Type:Original Article
- Keywords:
T1 Breast cancer;
Sentinel lymph node;
Sentinel lymphadenectomy
- MeSH:
Axilla;
Breast Neoplasms*;
Breast*;
Female;
Follow-Up Studies;
Frozen Sections;
Humans;
Liver;
Lymph Node Excision*;
Lymph Nodes;
Mastectomy, Segmental;
Mastectomy, Simple;
Neoplasm Metastasis;
Pathology;
Postoperative Complications;
Radiotherapy;
Recurrence;
Sentinel Lymph Node Biopsy
- From:Journal of Korean Breast Cancer Society
2003;6(4):263-270
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: This study was performed to evaluate the efficacy and safety of sentinel lymph node biopsy alone (SLNB) without axillary lymph node dissection. METHODS: Between Jun. 1999 and Dec. 2002, we carried out SLNB in 85 consecutive patients with T1 breast cancer whose sentinel lymph node(s) were tumor-free on intra- operative frozen section. Even when sentinel lymph node(s) turned out to be positive by permanent pathology, additional axillary lymph node dissection was not performed. Patients underwent total mastectomy or partial mastectomy and received an appropriate adjuvant therapy according to the characteristics of the primary tumor. All patients who had breast conserving surgery received postoperative radiotherapy to the remaining breast, but not to the axilla. RESULTS: SLNB only took 14 minutes and yielded no postoperative complications. Among the 85 patients whose sentinel lymph nodes were tumor-free on frozen section, 11 patients were diagnosed as metastatic in the permanent pathology. One of them had a macro-metastasized (2.5 cm) sentinel lymph node, and the rest had micro-metastasized sentinel lymph nodes. For 23.1 months of mean follow-up period, all the patients including a patient who died of liver metastases at 17 months showed no evidence of axillary recurrence. CONCLUSION: No axillary recurrence following SLNB suggests that SLNB may be a good alternative to routine axillary lymph node dissection while providing less surgical morbidity in women with a small breast cancer. However, more patients accumulation and follow-up period will be needed for the final conclusion.
