Characteristics of pediatric oral dosing and research progress in new dosage forms
- VernacularTitle:儿童口服用药特点及新剂型研究进展
- Author:
Fugen GU
1
Author Information
1. Dept. of Pharmacy，the Affiliated Hospital of Inner Mongolia Medical University，Hohhot 010050，China
- Publication Type:Journal Article
- Keywords:
oral dosing;
children;
special population;
new dosage forms;
compliance;
dosing device
- From:
China Pharmacy
2026;37(8):1099-1104
- CountryChina
- Language:Chinese
-
Abstract:
Children are a specific population of drug use and there exist obvious differences in anatomy， physiology and psycholo gy between children and adults. The development of child-appropriate oral dosage forms faces many challenges. Few types and specifications of oral dosage forms suitable for pediatric use lead to failure to meet the clinical need for pediatric dosing. In recent years， some child-appropriate new dosage forms， such as orodispersible mini-tablets， micro-tablets， oral dispersible films， oral multi-particulate dosage forms， oral powder， and chewable capsules， have been approved for marketing and further exhibit obvious clinical advantages. Meanwhile， other new pediatric oral preparations， such as drug-containing oral jelly， drug-containing milk powder， oral gel， preservative-free single-dose oral liquid preparations， and single-dose oral solid preparations that need to be reconstituted into liquid before use， may become an important supplement to pediatric oral preparations in the future. Additionally， the emergence of some new pediatric oral dosing devices will also provide a strong guarantee for convenient and accurate dosing in children.
