- VernacularTitle:克罗恩病肠狭窄纤维化的影像学评估进展
- Author:
Mengyuan ZHOU
1
;
Qingli ZHU
1
Author Information
- Publication Type:Review
- Keywords: inflammatory bowel disease; Crohn's disease; intestinal stenosis; cross sectional imaging; radiomics
- From: Medical Journal of Peking Union Medical College Hospital 2025;17(2):499-504
- CountryChina
- Language:Chinese
-
Abstract:
Intestinal stricture is a severe complication of Crohn's disease (CD), and the accurate differentiation of fibrotic strictures holds significant clinical value for guiding therapeutic decision-making. Due to the frequent difficulty in endoscopic passage caused by luminal narrowing, the assessment of lesions and tissue biopsy are often limited. In contrast, cross-sectional imaging techniques not only provide a comprehensive evaluation of intestinal lesions but also reveal extraintestinal changes, offering critical evidence for clinical decisions. With the rapid advancement of imaging technology, various novel radiological methods have emerged, providing new approaches for the assessment of intestinal fibrosis in CD strictures. Through a literature review, this article summarizes the latest research progress in advanced imaging techniques, including ultrasound elastography, magnetic resonance imaging(MRI) diffusion-weighted imaging, magnetization transfer MRI, and fibroblast activation protein inhibitor (FAPI)- positron emission computed tomography(PET). Additionally, it explores the potential applications and future directions of artificial intelligence and radiomics in the detection and grading of CD-associated fibrosis.

