Research progress on the relationship between levels of glucolipid metabolism indicators and risk of breast cancer
10.3969/j.issn.1006-2483.2026.02.030
- VernacularTitle:糖脂代谢指标水平与乳腺癌发病风险的研究进展
- Author:
Lichun LI
1
;
Hao WU
2
Author Information
1. Department of Outpatient, West China Hospital, Sichuan University, Chengdu , Sichuan 610041, China
2. Breast Center, West China Hospital, Sichuan University, Chengdu , Sichuan 610041, China
- Publication Type:Journal Article
- Keywords:
Glucose metabolism;
Lipid metabolism;
Breast cancer;
Onset risk;
Metabolic syndrome
- From:
Journal of Public Health and Preventive Medicine
2026;37(2):136-140
- CountryChina
- Language:Chinese
-
Abstract:
Breast cancer (BC) is a female malignant tumor with high incidence rate worldwide, and its disease burden continues to grow. Previous studies have demonstrated that there is a close association between changes of glucolipid metabolism indicators and risk of BC. Abnormal glucolipid metabolism may affect the occurrence and development of breast cancer by mediating chronic inflammatory states, affecting signaling pathways, promoting oxidative stress, affecting sex hormone levels and their biological activities, and driving endocrine dysfunction in adipose tissue. This paper systematically reviews the relationship between glucolipid metabolism indicators and risk of BC, aiming to point out the direction for further research on the relationship between glucolipid metabolism and BC, and to provide a reference basis for breast cancer risk assessment, early diagnosis, and prevention and treatment strategies.
