Relationship between uric acid, visceral fat thickness and insulin resistance in elderly patients with hypertriglyceridemia
10.3969/j.issn.1006-2483.2026.02.026
- VernacularTitle:老年高三酰甘油血症患者尿酸、内脏脂肪厚度与胰岛素抵抗的关系分析
- Author:
Yueping ZHAO
1
;
Qi ZHANG
1
;
Ming LIU
1
Author Information
1. Endocrinology Department, Chengdu Integrated TCM &Western Medicine Hospital, North District, Chengdu, Sichuan 610000, China
- Publication Type:Journal Article
- Keywords:
Elderly;
Hypertriglyceridemia;
Uric acid;
Visceral fat thickness;
Insulin resistance
- From:
Journal of Public Health and Preventive Medicine
2026;37(2):120-123
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between uric acid, visceral fat thickness and insulin resistance in elderly patients with hypertriglyceridemia (HTG). Methods A total of 347 elderly patients with HTG admitted to the hospital from January 2021 to January 2025 were retrospectively selected, and the related factors of insulin resistance in elderly HTG were analyzed. Results Among the 347 elderly patients with HTG, 218 cases had insulin resistance and 129 cases did not develop insulin resistance, and were included in the insulin resistance group (n=218) and the non-insulin resistance group (n=129) respectively. Compared with the non-insulin resistance group, patients in the insulin resistance group had higher proportions of severe HTG and concurrent fatty liver, higher levels of IL-6, TNF- α, FFA and uric acid, and thicker visceral fat thickness (P<0.05). After logistic regression analysis, it was found that the related factors for insulin resistance in elderly patients with HTG included the severity of HTG, IL-6, FFA, uric acid, and visceral fat thickness (P<0.05). Conclusion The severity of HTG, IL-6, FFA, uric acid, and visceral fat thickness are related to insulin resistance in elderly HTG patients. Clinically, it is necessary to pay attention to targeted interventions for uric acid control and visceral fat reduction in elderly patients with HTG so as to improve the insulin resistance status.