The relationship between triglyceride glucose-body mass index and cardiovascular and cerebrovascular diseases in middle-aged and elderly people
10.3969/j.issn.1006-2483.2026.02.025
- VernacularTitle:三酰甘油-葡萄糖-体重指数与中老年心脑血管疾病的关系
- Author:
Yuwei SONG
1
;
Yajun LIAN
1
Author Information
1. Department of General Practice, Affiliated Peace Hospital, Changzhi Medical College, Changzhi, Shanxi 046000, China
- Publication Type:Journal Article
- Keywords:
Elderly;
Triglycerides glucose-body mass index;
Cardiovascular and cerebrovascular diseases;
Correlation
- From:
Journal of Public Health and Preventive Medicine
2026;37(2):116-119
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the association between triglyceride glucose-body mass index (TyG-BMI) and the risk of cardiovascular and cerebrovascular diseases in middle-aged and elderly (aged≥45 years) people, and to provide a scientific basis for the prevention and control of cardiovascular and cerebrovascular diseases. Methods A total of 859 patients with cardiovascular and cerebrovascular diseases who were hospitalized in the Department of General Medicine of Heping Hospital affiliated to Changzhi Medical College from January 2020 to November 2024 were selected as the observation group, and 859 patients with non-cardiovascular and cerebrovascular diseases hospitalized during the same period were selected and matched 1:1 by age (±2 years) and gender as the control group. The TyG-BMI index was compared between the two groups，and the TyG-BMI was divided into three groups according to the control group quartile: low-level group (Q1:< P25), medium-level group (Q2:P25-P75), and high-level group (Q3:>P75). The relationship between the TyG-BMI and the risk of cardiovascular and cerebrovascular diseases was analyzed by conditional logistic regression. Results The TyG-BMI score in the case group was significantly higher than that in the control group (t=14.944，P<0.001), with the most significant difference in the age group of 45-55 years old (t=14.276, P<0.001). Multivariate logistic regression analysis showed that each unit increase in the TyG-BMI index was associated with a 1.406-fold increased risk of cardiovascular and cerebrovascular disease (95% CI: 1.231-2.301). The analysis of different index levels showed that compared with low-level TyG-BMI, the risk of cardiovascular and cerebrovascular diseases was higher at medium or high TyG-BMI. The subgroup analysis showed that the TyG-BMI index only had an effect on cardiovascular disease (OR=1.472, 95%CI: 1.141-3.032). Conclusion The TyG-BMI is positively correlated with the occurrence of cardiovascular and cerebrovascular diseases in middle-aged and elderly people, with a stronger association with cardiovascular disease.
