Clinical characteristics and prognostic factors of hypertriglyceridemia acute pancreatitis
10.3969/j.issn.1006-2483.2026.02.022
- VernacularTitle:高三酰甘油血症性急性胰腺炎临床特点及预后相关因素分析
- Author:
Yuanyuan LIU
1
;
Zhuo DIAO
1
;
Gang LI
1
;
Hongliang SHANG
1
;
Zhuo ZHANG
1
Author Information
1. Department of Gastroenterology, Hanzhong Central Hospital, Hanzhong, Shaanxi 723000, China
- Publication Type:Journal Article
- Keywords:
Hypertriglyceridemia acute pancreatitis;
Clinical characteristics;
Prognosis;
Related factors
- From:
Journal of Public Health and Preventive Medicine
2026;37(2):104-107
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical characteristics and related prognostic factors of hypertriglyceridemia acute pancreatitis (HTG-AP). Methods A retrospective analysis was conducted on 350 patients with HTG-AP admitted to HanZhong Central Hospital from March 2019 to March 2024. All patients received conventional treatment. They were followed up for one year after treatment. The prognosis of the patients was statistically analyzed, and logistic regression was used to analyze the related factors of prognosis. Results HTG-AP patients had an acute onset, with clinical symptoms of sudden upper abdominal pain (329/350), nausea and vomiting (275/350), acidosis (101/350), and multiple organ failure (38/350). All patients had elevated serum TG. During the follow-up period, 123 cases had a poor prognosis (poor prognosis group), and 227 cases had a good prognosis (good prognosis group). Compared with the good prognosis group, the patients in the poor prognosis group had higher levels of TG, creatinine and C-reactive protein at admission, lower levels of serum calcium and albumin, and higher proportions of diabetes mellitus history and severe conditions (P<0.05). Logistic regression analysis found that the factors related to the prognosis of patients with HTG-AP were TG level, C-reactive protein level, albumin level, history of diabetes mellitus, and moderate to severe condition (P<0.05). Conclusion HTG-AP patients have an acute onset and have main clinical symptoms of sudden upper abdominal pain, nausea and vomiting. Some patients experience systemic inflammatory reactions such as acidosis and multiple organ failure, and they may also have significantly increased serum TG. TG, C-reactive protein, albumin, history of diabetes mellitus, and severe disease conditions are associated with the prognosis of HTG-AP patients.
