Analysis of interlaboratory comparison results of 24-hour urinary sodium and potassium monitoring in China, 2023-2024
10.20001/j.issn.2095-2619.20251217
- VernacularTitle:全国2023—2024年24 h尿钠尿钾监测实验室间比对结果分析
- Author:
Huan LUO
1
;
Jing LIANG
;
Jinping ZHAO
;
Xiaoyan CHANG
;
Fanghong ZHAO
;
Xiaozhe TANG
Author Information
1. Occupational Health Institute of Beijing Center for Disease Control and Prevention, Beijing 100020, China
- Publication Type:Journal Article
- Keywords:
Urinary sodium;
Urinary potassium;
Verification;
Quality control;
Interlaboratory comparison;
Comparative analysis
- From:
China Occupational Medicine
2025;52(6):690-694
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the verification results of national laboratories involved in urinary sodium and potassium monitoring. Methods A total of 416 blinded verification samples from 32 monitoring laboratories, which participated in the national 24-hour urinary sodium and potassium detection verification comparison program in 2023 and 2024, were included as the study subjects. These samples were reanalyzed by both the monitoring laboratories and a reference laboratory using the ion-selective electrode method. Results The overall qualification rates for the 32 laboratories were 84.3% (182/216) in 2023 and 82.0% (164/200) in 2024, with 62.5% (20/32) achieving qualified results for two consecutive years. In 2023, centers for disease control and prevention (CDC) laboratories had higher qualification rates than the third-party laboratories for both 24-hour urinary sodium and potassium (95.2% vs 78.8%, 95.2% vs 75.8%, both P<0.05). This difference was not significant in 2024 (87.8% vs 78.0%, 90.2% vs 76.3%, both P>0.05). There was no significant difference in median absolute relative deviation of urinary sodium results from monitoring laboratories between 2023 and 2024 (2.7% vs 2.1%, P>0.05), whereas the median absolute relative deviation of urinary potassium results in 2024 was lower than that in 2023 (3.4% vs 8.4%, P<0.01). Conclusion The detection accuracy of national laboratories for urinary sodium and potassium monitoring shows an overall improving trend, with the accuracy of potassium measurement showing particular enhancement. There is no significant difference in the detection qualification rates between laboratories of the CDC and the third-party laboratories, suggesting that a sustained verification feedback mechanism is key to driving quality improvement.
