Determination of carbon disulfide in workplace air by portable gas chromatography-mass spectrometry
10.20001/j.issn.2095-2619.20251215
- VernacularTitle:便携式气相色谱-质谱法测定工作场所空气中二硫化碳
- Author:
Yan ZHANG
1
;
Xiaoyu HU
;
Jing ZHANG
;
Qiaozhen GUO
;
Jia FU
;
Lei ZHONG
;
Yedong GUO
;
Donglin LI
;
Dongdong CAO
;
Liu LIU
Author Information
1. Beijing Center for Diseases Prevention and Control Institute of Physical and Chemical Analysis, Beijing 100013, China
- Publication Type:Journal Article
- Keywords:
Workplace;
Air;
Internal standard method;
Carbon disulfide;
Portable;
Gas chromatography-mass spectrometry
- From:
China Occupational Medicine
2025;52(6):682-685
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a portable gas chromatography-mass spectrometry (GC-MS) method for determining carbon disulfide in workplace air. Methods Samples were collected using the built-in Tenax GR adsorption tube in the portable GC-MS, followed by thermal desorption. The analytes were separated on a DB-1 chromatographic column and detected by a 3D ion trap mass spectrometer, with 1,3,5-tris(trifluoromethyl)benzene used as the internal standard. Qualitative analysis was based on retention time and characteristic ions, and quantitative analysis was performed using the internal standard method. Results The method showed a linear range of 0.034-0.340 mg/m³ with a correlation coefficient of 0.999 4 using the adsorption tube enrichment mode. The detection limit was 0.007 mg/m³, and the lower limit of quantification was 0.022 mg/m³. The average recovery ranged from 97.5% to 104.0%. The within-run and between-run relative standard deviation was 2.7%-10.4% and 8.8%-14.8%, respectively. Conclusion A rapid, green, highly sensitive, and interference-resistant on-site detection method was established. As a supplement to existing national standard methods, this method is suitable for real-time monitoring of carbon disulfide in workplace air and for occupational exposure risk assessment.
