Determination of malononitrile in workplace air by solvent desorption- gas chromatography
10.20001/j.issn.2095-2619.20251214
- VernacularTitle:工作场所空气中丙二腈的溶剂解吸-气相色谱测定法
- Author:
Jiaheng HE
1
;
Guangkeng HU
;
Jiawen HU
;
Jing YUAN
;
Jinging QIU
;
Weifeng RONG
;
Banghua WU
Author Information
1. Guangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, Guangdong 510300, China
- Publication Type:Journal Article
- Keywords:
Workplace;
Air;
Malononitrile;
Solvent desorption;
Gas chromatography
- From:
China Occupational Medicine
2025;52(6):677-681
- CountryChina
- Language:Chinese
-
Abstract:
Objective To develop a solvent desorption-gas chromatography method for quantifying malononitrile in workplace air. Methods Malononitrile in workplace air was collected using a silica gel tube and desorbed with methanol. Separation was performed using DB-FFAP capillary column, and detection was performed by hydrogen flame ionization detector. Results The linear ranges of malononitrile were 4.00-600.00 mg/L, with the correlation coefficient of 0.999 92. The detection limit was 0.54 mg/L. The minimum detection concentration was 0.36 mg/m³ (based on a collected air volume of 1.5 L). The average desorption efficiency was 95.0%-101.0%. The within-run and between-run relative standard deviations were 0.9%-5.3% and 1.0%-6.8%, respectively. The sampling efficiency was 100.0%. The samples were stable at 4 ℃ for at least 14 days. Conclusion The solvent desorption-gas chromatography method established in this study for the determination of malononitrile in workplace air is simple to use, with high accuracy and good precision, and is suitable for the determination of malononitrile in workplace air.
