Short-Term Efficacy and Long-Term Recurrence Rate of Traditional Chinese Medicine Versus Western Surgical Treatment for Mixed Hemorrhoids：A Multi-Center Retrospective Cohort Study Based on Real-World Data
10.13288/j.11-2166/r.2026.07.009
- VernacularTitle:中医与西医手术操作治疗混合痔近期疗效及远期复发率的比较——基于真实世界数据的多中心回顾性队列分析
- Author:
Kang DING
1
;
Zhimin FAN
1
;
Xiaojie ZHOU
1
;
Xiaoxiao WANG
2
;
Yuanyuan GE
1
;
Huiting ZHU
1
;
Yuxin ZHU
1
;
Xia YANG
1
;
Jun DU
3
;
Shicai HUANG
4
;
Yang ZHANG
1
Author Information
1. Nanjing Hospital of Chinese Medicine affiliated to Nanjing University of Chinese Medicine，Nanjing，210022
2. Clinical Research Institute，Jiangsu Province Hospital of TCM
3. Suzhou Hospital of Traditional Chinese Medicine
4. Kunshan Integrated TCM and Western Medicine Hospital
- Publication Type:Journal Article
- Keywords:
mixed hemorrhoids;
excision of external hemorrhoids and ligation of internal hemorrhoids;
atrophied hemorrhoids injection;
internal hemorrhoid ligation
- From:
Journal of Traditional Chinese Medicine
2026;67(7):747-754
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the short-term and long-term efficacy of traditional Chinese medicine （TCM） surgical operations in treating mixed hemorrhoids. MethodsA multi-center retrospective cohort study was conducted， collecting clinical data from 17，831 mixed hemorrhoid surgery patients in 8 top-tier TCM hospitals in Jiangsu Province. Standardized and structured datasets were obtained through artificial intelligence models. Patients who underwent western surgical treatment were categorized into the western surgery group （11,646 cases）， and those receiving TCM surgical operations were categorized into the TCM surgery group （6185 cases）. Propensity score matching （1∶1 matching） was used to balance baseline data between groups. The primary outcome was the one-year recurrence rate， and secondary outcomes included the main symptoms （rectal bleeding， degree of prolapse） and secondary symptoms （anal distension， anal edema， wound secretion and exudation， anal stenosis， residual skin tags， perianal itching， and anal pain） measured on days 7， 28， and 60 after discharge. ResultsAfter matching， 2194 patients were included in each group. Symptom scores showed that at 28 days after discharge， the TCM surgical group had superior improvement in rectal bleeding ［OR=5.786， 95%CI （3.092，10.827）］， degree of prolapse ［OR=4.510， 95%CI （1.649，12.333）］， and anal edema ［OR=3.188， 95%CI （1.295，7.845）］ compared to the western surgical group. At 60 days post-discharge， the TCM group still showed advantages in improving rectal bleeding ［OR=5.237， 95%CI （1.077，25.464）］ and anal pain ［OR=11.697， 95%CI （1.186，115.336）］ （P＜0.05）. Long-term follow-up showed that the one-year recurrence rate in the TCM surgery group was 1.1% （8/726）， while that in the western surgery group was 2.3% （10/444）， with no statistically significant difference between the two groups （P＞0.05）. ConclusionBased on real-world data， TCM surgical treatment for mixed hemorrhoids shows significant short-term symptom improvement， particularly in terms of hemostasis， reducing swelling， and alleviating prolapse of anal masses.
