Research progress on the correlation between oral and esophageal microbiota and esophageal squamous cell ccarcinoma
10.19405/j.cnki.issn1000-1492.2025.08.028
- VernacularTitle:口腔和食管菌群与食管鳞癌相关性研究进展
- Author:
Jinyu Kong
1
Author Information
1. Henan Key Laboratory of Microbiome and Esophageal Cancer Prevention and Treatment ; Henan Key Laboratory of Cancer Epigenetics ; Cancer Hospital , The First Afiliated Hospital , and College of Clinical Medicine of Henan University of Science and Technology , Luoyang 471003；School of Information Engineering , Henan University of Science and Technology , Luoyang 471023
- Publication Type:Review
- Keywords:
sophageal squamous cell carcinoma (ESCC) being the predominant pathological type. The exact etiology of ESCC remains incompletely understood. With advances in 16S rRNA gene sequencing and metagenomics , microbial dys- biosis has been suggested to play a significant role in the pathogenesis of ESCC. Currently , research on the rela- tionship between microorganisms and ESCC is still in its early stages. This review summarizes the association be- tween oral and esophageal microbiota and ESCC , factors influencing microbial composition , and microbial commu- nities linked to ESCC prognosis , which may contribute to early detection and optimized treatment strategies for ES- CC.
- From:
Acta Universitatis Medicinalis Anhui
2025;60(8):1559-1565
- CountryChina
- Language:Chinese
-
Abstract:
Abstract:Esophageal cancer is one of the most common malignant tumors of the digestive system in China , with e-sophageal squamous cell carcinoma (ESCC) being the predominant pathological type. The exact etiology of ESCC remains incompletely understood. With advances in 16S rRNA gene sequencing and metagenomics , microbial dys- biosis has been suggested to play a significant role in the pathogenesis of ESCC. Currently , research on the rela- tionship between microorganisms and ESCC is still in its early stages. This review summarizes the association be- tween oral and esophageal microbiota and ESCC , factors influencing microbial composition , and microbial commu- nities linked to ESCC prognosis , which may contribute to early detection and optimized treatment strategies for ES- CC.
- Full text:2026041116492044622口腔和食管菌群与食管鳞癌相关性研究进展_孔金玉.pdf
