Research progress on ferroptosis and intestinal diseases
10.19405/j.cnki.issn1000-1492.2025.08.027
- VernacularTitle:铁死亡与肠道疾病的研究进展
- Author:
Xiaoge Wang
1
;
Zelun Li
2
;
Lijie Kang
2
;
Shibo Ma
2
;
Kaige Cui
2
;
Erping Xu
2
Author Information
1. Dept of Gastroenterology , The First Afiliated Hospital of Henan University of Chinese Medicine , Zhengzhou 450000;Henan Key Laboratory of Modern Research on Zhongjing ′s Herbal Formulae , Henan University of Chinese Medicine , Zhengzhou 450046)
2. Henan Key Laboratory of Modern Research on Zhongjing ′s Herbal Formulae , Henan University of Chinese Medicine , Zhengzhou 450046)
- Publication Type:Review
- Keywords:
colorectal cancer;
ischemia - reperfusion injury;
functional gastrointestinal disorders;
inflammatory bowel disease;
Ferroptosis;
mechanism
- From:
Acta Universitatis Medicinalis Anhui
2025;60(8):1554-1558，1565
- CountryChina
- Language:Chinese
-
Abstract:
Abstract:Ferroptosis , a novel , non-apoptotic form of cell death discovered in 2012 , has garnered significant at- tention. It is implicated in the pathogenesis and progression of various intestinal diseases , including colorectal canc- er, intestinal ischemia-reperfusion injury , functional gastrointestinal disorders , and inflammatory bowel disease. These processes involve multiple pathological mechanisms such as inflammation , immune dysregulation , and intesti- nal epithelial dysfunction. By reviewing and summarizing recent literature on ferroptosis-related mechanisms in in- testinal diseases , this article explores the roles and effects of ferroptosis in different intestinal pathologies.
- Full text:2026041116323445717铁死亡与肠道疾病的研究进展_王晓鸽.pdf
