The effect of endometriosis on pregnancy and delivery outcomes in cycles of single frozen euploid blastocyst transfer
10.19405/j.cnki.issn1000-1492.2025.08.026
- VernacularTitle:子宫内膜异位症对单个整倍体囊胚解冻移植周期 妊娠和分娩结局的影响
- Author:
Yuanyuan Zhang
1
;
Dehuan Huang
2
;
Yan Hao
3
;
Dawei Chen
3
;
Ping Zhou
3
;
Yunxia Cao
3
Author Information
1. Dept of Obstetrics and Gynecology, The First Afiliated Hospital of Anhui Medical University,Hefei 230022；Dept of Obstetrics and Gynecology, The Afiliated Hospital of Yan ′an University, Yan ’an 716200
2. Dept of Obstetrics and Gynecology, The First Afiliated Hospital of Anhui Medical University,Hefei 230022
3. Dept of Obstetrics and Gynecology, The First Afiliated Hospital of Anhui Medical University,Hefei 230022；Key Laboratory of Gametes and Reproductive Tract Abnormalities Research , National Health Commission , Hefei 230022 ; Key Laboratory of Reproductive Health and Genetics , Anhui Province , Hefei 230022 ; Anhui Province Life Resource Preservation and Artificial Organ Engineering Technology Research Center, Hefei 230022
- Publication Type:Journal Article
- Keywords:
endometriosis;
preimplantation genetic testing;
euploid;
frozen⁃thawed blastocyst transfer;
clinical pregnancy rate;
live birth rate
- From:
Acta Universitatis Medicinalis Anhui
2025;60(8):1548-1554
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the impact of endometriosis on pregnancy and delivery outcomes in patients undergoing single euploid frozen_thawed blastocyst transfer cycles following preimplantation genetic testing.
Methods :A retrospective analysis was performed on clinical data from patients undergoing frozen_thawed blastocyst transfer after preimplantation genetic testing at the reproductive center of The First Affiliated Hospital of Anhui Medical University. The endometriosis group comprised 84 treatment cycles. After 1 : 3 propensity score matching , 252 treatment cycles from non_endometriosis patients were included as the control group. General characteristics and clinical outcomes were compared between the two groups.
Results:There were no statistically significant differences between the two groups in terms of general characteristics , human chorionic gonadotropin ( HCG) positive rate , cycle clinical pregnancy rate per cycle , early miscarriage rate , preterm birth rate , live birth rate per cycle , cesarean section rate , delivery weeks , cumulative clinical pregnancy rate , and cumulative live birth rate (all P > 0. 05) .
Conclusion:Endometriosis may not reduce the pregnancy rate and live birth rate in single frozen euploid blastocyst transfer cycles .
- Full text:2026041116182348553子宫内膜异位症对单个整倍体囊胚解冻移植周期妊娠和分娩结局的影响_张媛媛.pdf
