Modified Morrow procedure for the treatment of hypertrophic obstructive cardiomyopathy: A single-center retrospective study in 318 patients
- VernacularTitle:改良Morrow术治疗肥厚型梗阻性心肌病318例的单中心回顾性研究
- Author:
Jie LI
1
,
2
;
Fan WENG
2
;
Nan CHEN
2
;
Yongxin SUN
2
;
Changfa GUO
2
;
Chunsheng WANG
2
;
Yi LIN
2
;
Wenjun DING
2
Author Information
1. Department of Cardiovascular Surgery, Huai'an Hospital Affiliated of Yangzhou University, Huai'an Fifth People's Hospital, Huai'an, 223300, Jiangsu, P. R. China
2. Department of Cardiovascular Surgery, Zhongshan Hospital Affiliated to Fudan University, Shanghai, 200000, P. R. China
- Publication Type:Journal Article
- Keywords:
Hypertrophic obstructive cardiomyopathy;
modified Morrow procedure;
systolic anterior motion;
Ⅲ° atrioventricular block;
left ventricular outflow tract obstruction;
septal myectomy
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2026;33(03):431-437
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the clinical efficacy of modified Morrow surgery in the treatment of hypertrophic obstructive cardiomyopathy. Methods A retrospective analysis was conducted on the clinical data of patients with hypertrophic obstructive cardiomyopathy treated with modified Morrow surgery at Zhongshan Hospital Affiliated to Fudan University from 2020 to 2023. Results A total of 318 patients were enrolled, including 156 males and 162 females, with an average age of (55.6±13.1) years. Preoperative echocardiography showed a mean interventricular septal thickness of (18.1±3.8) mm, peak left ventricular outflow tract pressure difference of (86.4±24.9) mm Hg. The surgery time was (162.3±51.0) min, extracorporeal circulation time was (80.9±31.0) min, and aortic occlusion time was (44.8±20.8) min. After the surgery, transesophageal echocardiography showed that the interventricular septal thickness was (11.0±1.8) mm and left ventricular outflow tract peak pressure difference was (9.4±5.1) mm Hg. The incidence rate of postoperative complete left bundle branch block was 45.3%, Ⅲ° atrioventricular block was 3.8%, and postoperative newly developed atrial fibrillation was 3.1%. The postoperative hospital stay was (6.6±4.9) days, and one perioperative death occurred, with a mortality rate of 0.3%. The follow-up time was (10.3±9.4) months, during which the transthoracic echocardiography revealed a ventricular septal thickness of (12.9±2.9) mm and a peak left ventricular outflow tract pressure difference of (13.9±10.0) mm Hg. Conclusion The modified Morrow procedure for the treatment of hypertrophic obstructive cardiomyopathy is safe and effective, with good results in the short and medium term.