Pathogenic bacteria distribution in patients with infectious eye diseases
10.3980/j.issn.1672-5123.2026.4.24
- VernacularTitle:感染性眼病患者病原菌分布特征分析
- Author:
Mingfeng FU
1
;
Ying HU
1
;
Lulu ZHAN
1
;
Houqun YING
1
Author Information
1. Department of Clinical Laboratory, Shangrao Central Hospital, Shangrao 334000, Jiangxi Province, China; Department of Clinical Laboratory, Shangrao Medical Center, the Second Affiliated Hospital of Nanchang University, Shangrao 334000, Jiangxi Province, China; Department of Clinical Laboratory, the First Affiliated Hospital of Jiangxi Medical College, Shangrao 334000, Jiangxi Province, China
- Publication Type:Journal Article
- Keywords:
eye infections;
pathogen distribution;
bacteria;
fungi;
Fusarium
- From:
International Eye Science
2026;26(4):694-699
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To analyze the characteristics of pathogenic bacteria in patients with infectious eye diseases at Shangrao Central Hospital from 2020 to 2024, providing a basis for the precise clinical prevention and control and the development of effective strategies.METHODS: A retrospective analysis was carried out on clinical specimens including the cornea, lacrimal duct, conjunctiva, and intraocular fluid samples, from patients with infectious eye diseases between May 2020 and December 2024. All the specimens underwent microbiological cultures and identification.RESULTS: A total of 447 patients enrolled ultimately in this study, including 250 males and 197 females, with an average age of 58.5±17.1 y. Among the 447 ocular specimens, bacterial infection was confirmed in 146 cases(32.7%). Of these positive samples, male patients accounted for 63.7%(93/146)and patients aged 51-70 y had the highest infection rate(88/146, 60.3%). Furthermore, migrant workers represented the predominant demographic affected by ocular infections, accounting for an overwhelming majority at 95.9%(140/146). When compared to other etiologies of disease, trauma emerged as the primary cause of ocular infections(P<0.01). In cases of bacterial ocular infections, Gram-positive cocci comprised approximately 61.2%, with Staphylococcus identified as the principal pathogen affecting the lacrimal duct, conjunctivae, and intraocular fluid. Streptococcus pneumoniae was found to be the main pathogen associated with corneal infections. Gram-negative bacteria were predominantly Pseudomonas aeruginosa. Fungal infections were observed in an alarming rate of 91.8% among corneal specimens. Fusarium was identified as the leading fungal pathogen responsible for these cases at a proportion of 45.9%.CONCLUSION: The distribution of pathogenic bacteria causing ocular infections demonstrates obvious tissue specificity. Trauma is identified as a major inducement of corneal fungal infection. Clinically, it is essential to pay particular attention to patients with ocular trauma, especially those engaged in agricultural labor who present with ocular infections, and fungal tests should be conducted as early as possible.
