Safety analysis of plasminogen activators in intraocular application
10.3980/j.issn.1672-5123.2026.4.16
- VernacularTitle:纤溶酶原激活剂在眼内应用的安全性分析
- Author:
Miao TANG
1
;
Jinsong ZHANG
1
;
Haisheng YU
1
Author Information
1. Shenyang Aier Eye Hospital,Shenyang 110000, Liaoning Province, China
- Publication Type:Journal Article
- Keywords:
plasminogen activator;
intraocular application;
safety analysis
- From:
International Eye Science
2026;26(4):646-650
- CountryChina
- Language:Chinese
-
Abstract:
Plasminogen activator is a kind of enzyme that plays a key role in the process of physiological hemostasis and thrombolysis. Its main function is to convert plasminogen into active plasmin, thereby initiating the dissolution of fibrin and maintaining blood mobility. This article discusses the safety of plasminogen activator in the intraocular application, elaborates on the types, structure, physiological function and mechanism of action of plasminogen activator in the eye. The analysis addresses the ocular tissue damage and systemic adverse reactions that may be caused by the application of plasminogen activator in the eye, and the risks and countermeasures combined with relevant research examples, aiming to provide reference for the safe application of plasminogen activator in clinical practice.
