Research progress of red light therapy for dry eye and visual fatigue
10.3980/j.issn.1672-5123.2026.4.14
- VernacularTitle:红光疗法治疗干眼与视疲劳的研究进展
- Author:
Yutong XIE
1
;
Siyu JIA
1
;
Jiamin GAO
1
;
Ruofan LIU
1
;
Meiling LI
1
;
Jiangying LI
1
;
Xi LUO
1
;
Xiaonan LI
1
;
Rong YAN
1
;
Hongbo LI
1
Author Information
1. Xi'an Medical University, Xi'an 710021, Shaanxi Province, China
- Publication Type:Journal Article
- Keywords:
dry eye disease;
red light therapy;
meibomian gland dysfunction;
mitochondrial oxidative stress;
color vision sensitivity;
resistance to blue light damage;
myopia prevention and control
- From:
International Eye Science
2026;26(4):636-640
- CountryChina
- Language:Chinese
-
Abstract:
Dry eye disease(DED)is a common ocular surface disorder worldwide, primarily characterized by a loss of homeostasis of the tear film, and frequently associated with meibomian gland dysfunction(MGD), decreased tear film stability, ocular discomfort, and visual impairment. In recent years, factors such as the widespread use of digital devices,the aging population, and environmental changes have contributed to a significant increase in its global prevalence, making it a major public health concern. Red light therapy(RLT), also known as low-level laser therapy(LLLT)or photobiomodulation(PBM), is a non-invasive treatment that utilizes low-energy red or near-infrared light to irradiate tissues. It exerts photobiomodulatory effects to promote cellular repair and functional recovery. This therapy has demonstrated considerable potential in treating various ocular conditions. Its broader clinical application could improve therapeutic outcomes, alleviate patient discomfort and financial burden, and reduce the consumption of healthcare resources, thereby yielding significant socio-economic benefits. This paper systematically reviews the multifaceted mechanisms and application prospects of RLT in managing DED, including its anti-inflammatory effects, improvement of meibomian gland function, promotion of conjunctival goblet cell repair, and alleviation of visual fatigue, aiming to provide a theoretical foundation and practical reference for its clinical adoption.