Analysis of factors influencing chronic cough following pulmonary surgery
- VernacularTitle:肺部手术后慢性咳嗽影响因素分析
- Author:
Yu WANG
1
;
Mingsheng WU
1
;
Gaoxiang WANG
1
;
Tian LI
1
;
Xianning WU
1
;
Xiaohui SUN
1
;
Meiqing XU
1
;
Yongfu ZHU
2
;
Shibin XU
1
;
Zhengwei CHEN
1
;
Mingran XIE
1
Author Information
1. Department of Thoracic Surgery, The First Affiliated Hospital of University of Science and Technology of China, Anhui Provincial Hospital, Hefei, 230001, P. R. China
2. Department of Oncology, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, 230031, P. R. China
- Publication Type:Journal Article
- Keywords:
Pulmonectomy;
chronic cough;
influence factors;
non-small cell lung cancer
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2025;32(11):1561-1566
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the risk factors for chronic cough following pulmonary surgery in patients with non-small cell lung cancer (NSCLC). Methods A retrospective analysis was conducted on 427 NSCLC patients who underwent pulmonary surgery in the Department of Thoracic Surgery, The First Affiliated Hospital of the University of Science and Technology of China, between January 2021 and June 2023. Patients were categorized into a chronic cough group (103 patients) and a non-chronic cough group (324 patients) based on the presence of cough at 8 weeks post-surgery. A comparative analysis was performed between the two groups, considering gender, age, smoking history, comorbidities, preoperative pulmonary function indicators, pleural adhesion, anesthesia duration, surgical site, operative techniques, lymph node dissection methods, tumor maximum diameter, and postoperative chest tube duration. Factors showing statistical significance in univariate analysis underwent multivariate logistic regression analysis. Results Among the 427 patients undergoing pulmonary surgery, there were 165 males and 262 females, with an average age of (59.93±12.11) years. The incidence of chronic cough was 24.12%. Univariate analysis revealed significant differences in smoking history, preoperative pulmonary function indicators, pleural adhesion, anesthesia duration ≥135.5 minutes, surgical site, operative techniques, lymph node dissection methods, tumor maximum diameter, and postoperative chest tube duration (P<0.05). Multivariate logistic regression analysis indicated that the surgical site (right upper lung), operative techniques (lobectomy), lymph node dissection, and anesthesia time ≥135.5 minutes were independent risk factors for chronic cough following pulmonary surgery. Conclusion Patients undergoing right upper lung surgery, lobectomy, lymph node dissection, and experiencing anesthesia duration ≥135.5 minutes are at a higher risk of developing chronic cough post-pulmonary surgery.
