Efficacy and safety of microwave ablation via different approaches for pulmonary nodules: A retrospective cohort study
- VernacularTitle:不同路径下微波消融术治疗肺结节疗效与安全性的回顾性队列研究
- Author:
Hao ZHANG
1
;
Shenyun SHI
1
;
Xinying LI
1
;
Rujia WANG
1
;
Lijun REN
1
;
Jingjing DING
1
;
Yonglong XIAO
1
;
Min YU
1
Author Information
1. Department of Respiratory and Critical Care Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210008, P. R. China
- Publication Type:Journal Article
- Keywords:
Electromagnetic navigation bronchoscopy;
microwave ablation;
pulmonary nodules;
efficacy;
safety
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2025;32(11):1554-1560
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the efficacy and safety of computed tomography (CT)-guided percutaneous versus electromagnetic navigation bronchoscopy (ENB)-guided microwave ablation (MWA) for the treatment of pulmonary nodules. Methods A retrospective analysis was conducted on the data of high-risk pulmonary nodule patients who underwent MWA at the Nanjing Drum Tower Hospital between 2022 and 2023. The pathological diagnosis rate, complications, and progression-free survival (PFS) rate were compared between the CT group and the ENB group. Results There were 61 patients in the CT group, including 30 males and 31 females, with an average age of (67.22±9.13) years. There were 53 patients in the ENB group, including 29 males and 24 females, with an average age of (65.29±13.76) years. The pathological diagnosis rate in the CT group was slightly higher than that in the ENB group (88.52% vs. 71.69%, P=0.03). However, the ENB group exhibited a lower incidence of perioperative complications, including pneumothorax (16.39% vs. 3.77%, P=0.03), hemoptysis (19.67% vs. 5.66%, P=0.05), and pain (22.95% vs. 7.55%, P=0.03). There was no statistically significant difference in PFS rate between the two groups [HR=1.17, 95%CI (0.23, 5.81), P=0.85]. Conclusion Both CT-guided and ENB-guided MWA are effective treatment modalities for high-risk pulmonary nodules.
