Imaging features of pulmonary nodules affecting lymph node metastasis in cT1-stage non-small cell lung cancer
- VernacularTitle:影响cT1期非小细胞肺癌淋巴结转移的肺结节影像学特征
- Author:
Jinlong ZHAO
1
;
Fengwei ZHANG
2
;
Dazhi JIANG
1
;
Cuiping YOU
3
;
Baotao LÜ
4
;
Minghui ZHANG
4
;
Hongwei GUO
5
;
Rong CHEN
1
;
Haiqin WANG
6
Author Information
1. Department of Thoracic Surgery, Linyi People s Hospital, Linyi, 276000, Shandong, P. R. China
2. Department of Cardiac Surgery, Linyi People s Hospital, Linyi, 276000, Shandong, P. R. China
3. Department of Clinical Laboratory, Linyi People s Hospital, Linyi, 276000, Shandong, P. R. China
4. Department of Radiology, Linyi People s Hospital, Linyi, 276000, Shandong, P. R. China
5. Department of Pathology, Linyi People s Hospital, Linyi, 276000, Shandong, P. R. China
6. Department of Rehabilitation, Linyi People s Hospital, Linyi, 276000, Shandong, P. R. China
- Publication Type:Journal Article
- Keywords:
Non-small cell lung cancer;
pulmonary nodule;
imaging features;
prediction model;
lymph node metastasis
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2025;32(11):1547-1553
- CountryChina
- Language:Chinese
-
Abstract:
Objective To use imaging features of pulmonary nodules to predict the risk of lymph node metastasis in patients with cT1-stage non-small cell lung cancer (NSCLC), providing a reference for clinical decision-making. Methods A retrospective analysis was conducted on the imaging features and postoperative pathological results of cT1 NSCLC patients who underwent surgical treatment at Linyi People’s Hospital from July 2019 to July 2022. Patients were grouped and analyzed according to lymph node metastasis status. Results A total of 1 123 patients were included, comprising 471 males and 652 females, with a median age of 59 (52, 66) years. Comparative analysis revealed that sex, age, nodule location, nodule size on imaging, solid component size, consolidation tumor ratio (CTR), average CT value, and tumor proximity to the pleura all influenced lymph node metastasis. A nomogram was constructed, indicating that the probability of lymph node metastasis in cT1 NSCLC was positively correlated with solid component size, CTR, and average CT value of the pulmonary nodule, and negatively correlated with patient age. The area under the receiver operating characteristic curve was 0.929. Conclusion For cT1 NSCLC patients, the probability of lymph node metastasis can be predicted by measuring the solid component size, CTR, and average CT value of the pulmonary nodule, in conjunction with patient age. However, relying solely on pulmonary nodule imaging characteristics is insufficient to determine a specific lymph node dissection strategy.
