Clinical efficacy and safety of remote ischaemic preconditioning in selective vascular surgery: A systematic review and meta-analysis
- VernacularTitle:远端缺血预处理在选择性血管手术中临床疗效及安全性的系统评价与Meta分析
- Author:
Guangzu LIU
1
;
Hongxu LIU
1
;
Zhili WEI
1
;
Hao CHEN
1
;
Yalan ZHANG
2
;
Shuai DONG
2
;
Bing SONG
1
,
2
Author Information
1. The First School of Clinical Medicine, Lanzhou University, Lanzhou, 730000, P. R. China
2. Department of Cardiovascular Surgery, The First Hospital of Lanzhou University, Lanzhou, 730000, P. R. China
- Publication Type:Journal Article
- Keywords:
Remote ischaemic preconditioning;
elective vascular surgery;
clinical efficacy;
systematic review/meta-analysis
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2025;32(10):1487-1494
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically evaluate the clinical effects of remote ischaemic preconditioning (RIPC) in elective vascular surgery. Methods Electronic searches were conducted in The Cochrane Library, PubMed, EMbase, Web of Science, CNKI, Wanfang Data, VIP Database, and CBM. Relevant randomized controlled trials (RCTs) were screened according to inclusion and exclusion criteria. Meta-analysis was performed using RevMan 5.3 software, and the risk of bias was assessed using the Cochrane risk of bias tool. Results A total of 15 studies involving 1 382 patients were included. The meta-analysis results showed no statistically significant difference between RIPC and non-RIPC groups in reducing perioperative mortality in elective vascular surgery (P>0.05). There were also no statistically significant differences between the two groups of vascular surgery patients regarding the incidence of myocardial infarction, renal injury, postoperative stroke, postoperative length of hospital stay, duration of surgery or total anesthesia time, or the incidence of limb injury, arrhythmia, heart failure, and pneumonia (P>0.05). Conclusion For patients undergoing elective vascular surgery, there are no significant differences between RIPC and non-RIPC in terms of perioperative mortality and other clinical endpoint outcomes.
