Advances in platelet-associated membrane delivery systems
10.13303/j.cjbt.issn.1004-549x.2026.02.017
- VernacularTitle:血小板相关膜递送系统的研究进展
- Author:
Ting PAN
1
;
Li CHEN
2
;
Chunyan YAO
3
Author Information
1. Department of Blood Transfusion, The First Affiliated Hospital (Southwest Hospital) of Army Medical University, Chongqing 400038, China; Department of Blood Transfusion, The Second Affiliated Hospital (Xinqiao Hospital) of Army Medical University, Chongqing 400037, China
2. Department of Blood Transfusion, The Second Affiliated Hospital (Xinqiao Hospital) of Army Medical University, Chongqing 400037, China
3. Department of Blood Transfusion, The First Affiliated Hospital (Southwest Hospital) of Army Medical University, Chongqing 400038, China
- Publication Type:Journal Article
- Keywords:
platelet membrane;
cell membrane-coated biomimetic delivery systems;
nanomaterials;
targeted therapy
- From:
Chinese Journal of Blood Transfusion
2026;39(2):277-284
- CountryChina
- Language:Chinese
-
Abstract:
Progress in biomimetic membrane systems has enabled the extensive application of cell membranes in constructing nano-drug delivery systems. These biological membranes endowed the delivery systems with advantages, including superior biocompatibility, precision targeting capabilities, and long circulation. Platelet membranes, owing to their distinctive biological properties, have emerged as exceptional natural materials for nano-drug delivery systems and have continuously promoted the development of the delivery systems in the field of disease treatment. This review comprehensively summarizes the biological characteristics and molecular basis of platelet-associated membranes, various coated systems and methods, and systematically summarizes the research progress of platelet-related membrane delivery systems in the treatment of tumors, inflammatory diseases, cardiovascular and cerebrovascular diseases, and thrombotic diseases. It also analyzes the application challenges in the biomedical field and looks forward to the future development direction.
