Management of prevention and treatment of chronic diseases after kidney transplantation
10.12464/j.issn.1674-7445.2025309
- VernacularTitle:肾移植术后慢性病防治管理
- Author:
He ZHANG
1
;
Xiaopeng HU
1
Author Information
1. Department of Urology, Beijing Chaoyang Hospital Affiliated to Capital Medical University, Beijing 100020, China.
- Publication Type:Editorial
- Keywords:
Kidney transplantation;
Chronic disease;
End-stage renal disease;
Immunosuppression;
Graft dysfunction;
Precision medicine;
Immune regulation;
Dynamic prevention and treatment
- From:
Organ Transplantation
2026;17(2):192-197
- CountryChina
- Language:Chinese
-
Abstract:
Kidney transplantation is the most ideal treatment method for end-stage renal disease, significantly improving the survival rate and quality of life of patients. However, as the postoperative survival period gradually lengthens, chronic diseases have become the main obstacle affecting the long-term outcome of kidney transplantation. These chronic diseases have a high incidence, involve multiple organs and significantly impact prognosis. The core driving factors are mainly related to long-term immunosuppressive therapy. This article systematically discusses the occurrence mechanisms, prevention and treatment strategies, and classification management of common chronic diseases after kidney transplantation (mainly including chronic graft dysfunction, cardiovascular diseases, infections, malignant tumors, bone metabolism disorders, etc.). At the same time, it explores future development directions such as precision medicine, new immune modulators and remote management, emphasizing a comprehensive management model centered on "multidisciplinary collaboration + individualized treatment + continuous monitoring" to achieve long-term, systematic, and dynamic prevention and treatment of chronic diseases for kidney transplant recipients.