Dosimetric comparison and analysis of AXB and AAA algorithms in postoperative radiotherapy planning for left-sided breast cancer after breast-conserving surgery
10.13491/j.issn.1004-714X.2026.01.020
- VernacularTitle:AXB与AAA算法在左侧乳腺癌保乳术后放疗计划中的剂量学对比及分析
- Author:
Jianhui WU
1
;
Yufeng GAO
2
;
Kai GAO
1
;
Chengqiong TANG
3
;
Jiao LIU
4
Author Information
1. Ili & Jiangsu Joint Institute of Health; The Friendship Hospital of Ili Kazakh Autonomous Prefecture, Yining 835000, China.
2. The 946 th Hospital of the People's Liberation Army, Yining 835000, China.
3. The Affiliated Tumor Hospital of Xinjiang Medical University, Urumqi 830000, China.
4. Bayingolin Mongolian Autonomous Prefecture People's Hospital, Korla 84100, China.
- Publication Type:OriginalArticles
- Keywords:
Breast cancer;
Radiotherapy;
Dosimetry;
AXB algorithm;
AAA algorithm
- From:
Chinese Journal of Radiological Health
2026;35(1):120-127
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the impact of two different algorithms, AAA and AXB, on the dose distribution of postoperative radiotherapy for left-sided breast cancer after breast-conserving surgery. Methods A total of 96 target volumes from patients who underwent breast-conserving surgery for left-sided breast cancer were selected for dose verification using a two-dimensional matrix system. The planned dose distributions were simulated using both AAA and AXB algorithms. Dosimetric differences in organs at risk and the target volumes were then compared to identify the algorithm that could reduce the radiation dose to organs at risk without compromising the dose distribution to the target volume. Dose verification was performed on the plans generated by both algorithms, and the pass rates of plans for each target volume using both algorithms were compared to provide a quantitative basis for the precise selection of subsequent radiotherapy plans. Results Both AAA and AXB plans met the radiotherapy requirements. The AXB algorithm demonstrated significant advantages in the D98, D2, homogeneity index, and conformity index for the planning target volume, as well as in the V5 and V20 for the left lung. The AXB algorithm showed advantages in the V30 for the heart and the maximum and mean doses for the skin. With the 2 mm/2% criterion in dose verification, the gamma pass rate was higher for the AXB algorithm. Conclusion Through a comparative analysis of the two algorithms, this study revealed that the AXB algorithm offers certain advantages in the dose distribution of radiotherapy after breast-conserving surgery for left-sided breast cancer. These findings provide an important reference for the rational selection of algorithms in clinical practice and are expected to improve radiotherapy efficacy and patient prognosis.
