Value of bedside ultrasound monitoring of quadriceps muscle changes in mechanically ventilated children in the early treatment of ICU-acquired muscle weakness
10.13491/j.issn.1004-714X.2026.01.017
- VernacularTitle:床旁超声监测机械通气患儿股四头肌变化在早期治疗ICU获得性肌无力的价值
- Author:
Zhijun LAI
1
;
Wenhai YANG
1
;
Yan LI
1
;
Lifen GU
1
;
Keze MA
1
Author Information
1. PICU, Dongguan Children’s Hospital, Guangdong Medical University, Dongguan 523325, China.
- Publication Type:OriginalArticles
- Keywords:
ICU-acquired muscle weakness;
Mechanical ventilation;
Bedside ultrasound;
Quadriceps muscle;
Children
- From:
Chinese Journal of Radiological Health
2026;35(1):103-107
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the application value of bedside ultrasound monitoring of quadriceps muscle changes in mechanically ventilated children in the early treatment of ICU-acquired muscle weakness (ICU-AW). Methods Eighty-two pediatric ICU patients with mechanical ventilation for>48 hours were selected. On the day of admission (D0) and on day 7 (D7), bedside ultrasound was performed to measure the thickness and cross-sectional area of the rectus femoris and vastus intermedius muscles. Patients were classified using Medical Research Council scores into control group (n = 63) and muscle weakness group (n = 19). Muscle parameters and atrophy rates were compared between groups. Diagnostic performance was assessed using receiver operating characteristic curves. Results The incidence of ICU-AW was 23.17%. At both D0 and D7, the average thickness of the rectus femoris, the average thickness of the vastus intermedius, the average area of the rectus femoris, and the average area of the vastus intermedius were significantly different between the two groups (P<0.05). The atrophy rates of the thickness of the rectus femoris and the area of the vastus intermedius were lower in the control group than in the muscle weakness group at both D0 and D7 (P<0.05). The area under the receiver operating characteristic curve for quadriceps parameters in diagnosing ICU-AW was 0.871, with a sensitivity of 89.47% and a specificity of 79.37%. Conclusion Bedside ultrasound dynamic monitoring of quadriceps changes enables early identification of ICU-AW and provides a basis for clinical intervention.
