Research progress on bone morphogenetic proteins and oral squamous cell carcinoma
10.19405/j.cnki.issn1000-1492.2025.10.028
- VernacularTitle:骨形态发生蛋白与口腔鳞状细胞癌的研究进展
- Author:
Fu ’ao Xing
1
;
Faming Tian
2
;
Qiangqiang Lian
2
;
Xinhao Fan
3
Author Information
1. School of Stomatology , North China University of Science and Technology, Tangshan 063000
2. School of Public Health , North China University of Science and Technology, Tangshan 063000
3. Dept of Stomatology , Kailuan General Hospital Afiliated to North China University of Science and Technology, Tangshan 063000
- Publication Type:Review
- Keywords:
bone morphogenetic proteins;
oral squamous cell carcinoma;
prognosis;
tumor metastasis;
tumor invasion;
molecular mechanism
- From:
Acta Universitatis Medicinalis Anhui
2025;60(10):1979-1983
- CountryChina
- Language:Chinese
-
Abstract:
Abstract:Oral cavity cancer is the sixth-leading cancer worldwide, which has become one of the important factors affecting oral health. The morbidity of oral squamous cell carcinoma(OSCC) accounts for nearly 80% of oral cavity cancer. The pathogenesis and prevention of OSCC have become a hot topic in this field. Previous studies have shown that bone morphogenetic proteins(BMPs) participated in the development, invasion and metastasis of gastric and bone cancers, thereby impacting the prognosis of the patients. Recent studies have found that BMPs also play a key role in the development, progression, metastasis, and invasion of OSCC, This review therefore summarizes the correlation and molecular mechanism between BMPs and the biological behavior of OSCC.
- Full text:2026031100002544066骨形态发生蛋白与口腔鳞状细胞癌的研究进展_邢付奥.pdf
