Clinical efficacy of cranial electrotherapy stimulation in chronic insomnia : a research study
10.19405/j.cnki.issn1000-1492.2025.11.021
- VernacularTitle:经颅微电流刺激在慢性失眠中的临床疗效
- Author:
Jiajia Jiao
1
;
Jialu Li
1
;
Xixi Sun
1
;
Yunfei Yin
1
;
Chengjuan Xie
1
Author Information
1. Dept of Neurology , The First Afiliated Hospital of Anhui Medical University, Hefei 230022
- Publication Type:Journal Article
- Keywords:
chronic insomnia;
cranial electrotherapy stimulation;
sleep quality;
current frequency;
all-night polysomnography
- From:
Acta Universitatis Medicinalis Anhui
2025;60(11):2144-2153
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effects of cranial electrotherapy stimulation(CES) with varying parameter configurations on sleep quality in patients diagnosed with chronic insomnia disorder.
Methods:Seventy-two participants meeting diagnostic criteria for chronic insomnia disorder were randomly allocated to a four-arm parallel study design.The intervention protocol comprised:Group 1(G1) received CES at 0.5 Hz,300 μA;Group 2(G2) underwent CES treatment at 1.5 Hz,300 μA;Group 3(G3) administered 100 Hz,300 μA stimulation;and Group4(G4) received sham stimulation with identical device placement but no current delivery.Primary outcomes were quantified through polysomnography(PSG) recordings conducted at baseline and post-intervention,whereas secondary outcomes were assessed via standardized sleep questionnaires including the Pittsburgh sleep quality index(PSQI) and Insomnia Severity Index(ISI).
Results:Following a 10-day intervention protocol,significant clinical improvements were observed across all active treatment groups(G1-G3) as evidenced by reductions in PSQI.Insomnia severity index(ISI) scores quantitative polysomnographic analysis revealed that both G2(1.5 Hz) and G3(100 Hz) cohorts demonstrated statistically significant enhancements in Flinders Fatigue Scale(FFS) scores,total sleep time(TST),and sleep efficiency(SE),accompanied by reduced sleep onset latency(SOL) compared to baseline measurements.However,no statistically significant differences were detected between the G2 and G3 intervention arms across all measured parameters.CES exerted no significant effect on sleep architecture.
Conclusion:CES can effectively improve the sleep of patients with chronic insomnia.Within a certain range,a higher frequency of CES leads to better sleep improvement effects.
- Full text:2026030513053021012经颅微电流刺激在慢性失眠中的临床疗效_焦佳佳.pdf
