Surveillance and analysis of measles, rubella and mumps antibody levels among healthy people in Fengtai District of Beijing City,2024
10.13200/j.cnki.cjb.004644
- VernacularTitle:2024年北京市丰台区健康人群麻疹、风疹及流行性腮腺炎抗体水平监测分析
- Author:
Xiaofei JIANG
1
Author Information
1. Beijing Fengtai District Center for Disease Control and Prevention (Beijing Fengtai District Health Supervision Institute), Beijing 100070, China
- Publication Type:Journal Article
- Keywords:
Healthy people;
Measles;
Rubella;
Mumps;
Antibody levels
- From:
Chinese Journal of Biologicals
2026;39(02):162-166+173
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the antibody levels of measles, rubella and mumps among healthy residents in Fengtai District, Beijing, and to provide reference for further improving the level of immunization coverage.Methods A total of 242 healthy people who had continuously resided in Fengtai District for more than six months were randomly selected. Blood samples were collected for quantitative detection of IgG antibodies against measles, rubella and mumps by indirect ELISA.Results Among the 242 people surveyed, the positive rates of measles, rubella and mumps antibodies were 76. 45%, 89. 67%and 75. 62%, and the geometric mean concentrations(GMCs) were 739. 97 IU/L, 35. 87 IU/mL and 43. 01 RU/mL,respectively. There was no significant difference in the positive rates of measles, rubella, and mumps antibodies between males and females(χ~2= 0. 659, 0. 173 and 0. 046, respectively, P > 0. 05). There was no significant difference in the positive rates of measles, rubella, and mumps antibodies between this city and floating household registrations(χ~2= 1. 859, 0. 045 and 1. 098, respectively, P > 0. 05). However, the positive rates of measles, rubella, and mumps antibodies between different age groups were statistically significantly different(χ~2= 31. 324, χ~2_(fisher)= 28. 650, χ~2= 24. 817, P < 0. 05), and the positive rates of three antibodies were statistically significantly different among different immunization times(χ~2= 14. 315, χ~2_(fisher)=21. 766, χ~2= 17. 764, P < 0. 05).Conclusion The levels of measles, rubella and mumps antibodies among healthy individuals in Fengtai District remain to be further enhanced. In the future, routine vaccination services should be continuously strengthened, and women of childbearing age should be advocated to receive measles-mumps-rubella vaccine, so as to further enhance the level of immunization coverage.
