The efficacy of oral solution of magnesium sodium potassium sulfate in bowel preparation before colonoscopy
10.12206/j.issn.2097-2024.202311049
- VernacularTitle:硫酸镁钠钾口服液在内镜肠道清洁准备中的效果
- Author:
Xin HUANG
1
;
Rujie YANG
1
;
Feng QIN
1
;
Shilian ZHANG
1
;
Xin WU
1
;
Xiaoyan YIN
1
Author Information
1. Department of Gastroenterology, b. Department of Emergency, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.
- Publication Type:Originalarticles
- Keywords:
bowel preparation;
colonoscopy;
oral sulfate solution;
polyethylene glycol
- From:
Journal of Pharmaceutical Practice and Service
2026;44(2):85-87
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the efficacy and safety of oral solution of magnesium sodium potassium sulfate in bowel preparation before colonoscopy. Methods Patients who planned to undergo colonoscopy at the digestive department of the Ninth People’s Hospital, affiliated to School of Medicine of Shanghai Jiao Tong University from January 2023 to August 2023 were selected and eligible subjects were divided into two groups: Group A took polyethylene glycol （PEG） and Group B took oral solution of magnesium sodium potassium sulfate （OSS）. The quality, drug tolerance, and safety of intestinal preparation were evaluated. The quality of bowel preparation was evaluated by the boston bowel preparation scale （BBPS）. Results The right colon BBPS score of Group B was (2.39±0.82) points, which was significantly higher than of Group A (2.11±0.43) points （P<0.05）. The overall score of Group B was higher than that of Group A （P<0.05）. OSS was easier to take than PEG, with a good taste and overall sensation. Patients were willing to use OSS to clean their bowels even when they were willing to undergo another examination （P<0.05）. There was a significant difference in nausea and vomiting symptoms between the two groups （P<0.05）, and there were no significant changes in renal function and electrolytes before and after medication in the two groups of patients. Conclusion OSS had a higher quality of bowel cleaning and was easier for patients to accept.
