Current situation of disease perception in patients with tophi and its correlation with quality of life
10.3969/j.issn.1006-2483.2026.01.040
- VernacularTitle:痛风石性患者疾病感知现状及其与生活质量的相关性
- Author:
Xiaoxiao WANG
1
;
Pinpin ZHANG
1
;
Qing HUANG
1
;
Yuheng YANG
1
Author Information
1. Department of Rheumatology and Immunology, Shanghai Sixth People's Hospital, Shanghai 200233, China
- Publication Type:Journal Article
- Keywords:
Gout;
Disease perception;
Tophi;
Quality of life
- From:
Journal of Public Health and Preventive Medicine
2026;37(1):183-186
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the current situation of disease perception in patients with tophi and its correlation with the quality of life. Methods A retrospective analysis was conducted on 303 gout patients admitted to the Shanghai Sixth People's Hospital from January 2023 to December 2024. The patients were classified into tophi gout (n=150) and non-tophi gout (n=153) groups based on whether they were tophi gout or not. The current disease perception status and quality of life of the two groups were compared using Simplified Chinese Version of the Disease Cognition Questionnaire (BIPQ) and Short Form of Health Survey (SF-36). Logistic regression was used to analyze the influencing factors of the quality of life of patients with tophi gout. Results Compared with the non-tophaceous gout group, the tophaceous gout group had a higher BIPQ score, and a lower SF-36 score (P<0.05). Among patients with tophaceous gout, 80 cases had good quality of life, and 70 cases had poor quality of life. These patients were included in the good quality of life group (n=80) and the poor quality of life group (n=70), respectively. Compared with the good quality of life group, patients in the poor quality of life group had longer gout course and average duration of each gout attack, as well as higher 20-item tophi impact questionnaire (TIQ-20) score and BIPQ score (P<0.05). Logistic regression analysis showed that the course of gout (OR=1.070, 95% CI: 1.017-1.126, P=0.009), TIQ-20 score (OR=1.048, 95% CI: 1.022-1.075, P<0.001), and BIPQ score (OR=1.055, 95%CI: 1.009-1.104, P=0.019) were risk factors affecting the quality of life in patients with tophaceous gout (P<0.05). Conclusion The course of gout, TIQ-20 score and BIPQ score are risk factors affecting the quality of life of patients with tophi gout.
