Risk factors for type 2 diabetes mellitus with metabolic-associated fatty liver disease and their relationship with BMI management
10.3969/j.issn.1006-2483.2026.01.022
- VernacularTitle:2型糖尿病合并代谢相关脂肪性肝病的风险因素及与BMI管理的关系
- Author:
Xi CHEN
1
;
Jing ZHANG
1
;
Yang LIU
2
Author Information
1. Department of Health Examination, 363 Hospital, Chengdu, Sichuan 610041, China
2. Department of Nursing, 363 Hospital, Chengdu, Sichuan 610041, China
- Publication Type:Journal Article
- Keywords:
Type 2 diabetes mellitus;
Metabolic-associated fatty liver disease;
Risk factors;
BMI management
- From:
Journal of Public Health and Preventive Medicine
2026;37(1):108-111
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the risk factors of type 2 diabetes mellitus (T2DM) with metabolic-associated fatty liver disease (MAFLD) and explore their relationship with BMI management. Methods A retrospective analysis was conducted of 310 patients with type 2 diabetes who underwent physical examinations at the 363 hospital between March 2023 and March 2025. Among these patients, those with MAFLD were counted. The risk factors of T2DM with MAFLD were analyzed by logistic regression analysis. The relationship between T2DM with MAFLD and BMI management was explored by Spearman correlation coefficient analysis. Results Compared with the non-MAFLD group, the levels of alanine aminotransferase (ALT), fasting insulin (I0), fasting blood glucose (G0), BMI, triglyceride (TG), aspartate aminotransferase (AST), and serum uric acid (SUA) were higher while the level of high-density lipoprotein cholesterol (HDL-C) was lower in the MAFLD group (P<0.05). Logistic regression analysis showed that BMI, SUA, I0, ALT, G0, and BMI control scale score were risk factors of T2DM with MAFLD (P<0.05). The score of BMI control scale of patients in the MAFLD group was higher than that in the non-MAFLD group (P<0.05). Correlation analysis indicated that T2DM with MAFLD was negatively correlated with BMI management (P<0.05). Conclusion BMI, SUA, I0, ALT, and G0 are all risk factors of T2DM with MAFLD. BMI management is negatively correlated with T2DM with MAFLD. Patients with T2DM should control BMI and blood glucose to reduce the occurrence of MAFLD.