Current applications and research progression of central nervous system adaptation in rehabilitation of ophthalmic diseases
10.3980/j.issn.1672-5123.2026.3.14
- VernacularTitle:中枢神经适应性在眼病治疗中的应用现状及研究进展
- Author:
Benzhang LI
1
;
Jian ZHOU
1
Author Information
1. Department of Ophthalmology, Xijing Hospital, Air Force Medical University;Eye Institute of PLA, Xi'an 710032, Shaanxi Province, China; Department of Ophthalmology, No.962 Hospital of the Joint Logistic Support Force of the People's Liberation Army of China, Harbin 150300, Heilongjiang Province, China
- Publication Type:Journal Article
- Keywords:
central nervous system adaptation;
amblyopia;
cataract;
glaucoma;
age-related macular degeneration
- From:
International Eye Science
2026;26(3):447-451
- CountryChina
- Language:Chinese
-
Abstract:
Central nervous system adaptation represents a core compensatory mechanism whereby the nervous system dynamically adjusts structure and function to counteract pathological damages, relying on the synergistic effects of multi-level neural plasticity. Amblyopia training may enhance cortical function through dichoptic augmented reality and visual attention exercises, cognitive training and neuroimmunomodulation may facilitate multifocal intraocular lens adaptation after cataract surgery, transcranial alternating current stimulation may improve visual fields in glaucoma, and perceptual learning may optimize eccentric fixation in age-related macular degeneration rehabilitation. These therapeutic approaches may shift the focus of managements from traditional structural repair to neural functional remodeling in ophthalmic diseases, which will open a new way for enhancing patients' visual function and quality of vision. This review aims to systematically review the mechanisms underlying central nervous system adaptability, its current applications in ocular disease rehabilitation and future prospects.
