Pathogenetic Evolution of Deficiency，Dampness，and Blood Stasis in Rheumatoid Arthritis and Its Staged Treatment
10.13288/j.11-2166/r.2026.04.019
- VernacularTitle:类风湿关节炎的虚、湿、瘀病机演变及分期辨治
- Author:
Chibin LIU
1
;
Yihong YANG
1
;
Shudian XIONG
1
;
Haifang DU
1
;
Maojie WANG
1
;
Xiumin CHEN
1
;
Runyue HUANG
1
Author Information
1. The Second Clinical Medical College of Guangzhou University of Chinese Medicine/National Key Laboratory of Research on Traditional Chinese Medicine Syndrome，Guangzhou，510120
- Publication Type:Journal Article
- Keywords:
rheumatoid arthritis;
deficiency;
dampness;
blood stasis
- From:
Journal of Traditional Chinese Medicine
2026;67(4):461-464
- CountryChina
- Language:Chinese
-
Abstract:
It is proposed that the pathogenesis of rheumatoid arthritis （RA） is centered on deficiency， dampness， and blood stasis， which interact with and evolve into one another during the onset and progression of the disease. The development of RA is closely associated with insufficiency of healthy qi and the interbinding of dampness and blood stasis. Accordingly， treatment emphasizes an integrated approach that combines tonifying deficiency， eliminating dampness， and resolving blood stasis， and is implemented in three main stages. In the initial stage， therapy focuses on supporting healthy qi， dispelling dampness， and relieving impediment， with modified Huangqi Guizhi Wuwu Decoction （黄芪桂枝五物汤） combined with Yiyiren Decoction （薏苡仁汤）. In the active stage， treatment aims to eliminate dampness， resolve blood stasis， and unblock the collaterals， using modified Wutou Decoction （乌头汤） or Guizhi Shaoyao Zhimu Decoction （桂枝芍药知母汤）. In the remission stage， therapy emphasizes strengthening the spleen and reple-nishing qi to prevent recurrence， with modified Shenling Baizhu Powder （参苓白术散） combined with Guipi Decoction （归脾汤）.
