Current Research Status，Challenges，Differentiation and Treatment Strategies of Traditional Chinese Medicine for Gastroesophageal Reflux Disease

Fengyun WANG; Mi LYU; Bingduo ZHOU; Beihua ZHANG; Yi WANG; Tingting XU; Cong HE; Xiaokang WANG; Xin LIU; Yang WANG; Kaiyue HUANG; Lusi XU; Xudong TANG

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Current Research Status，Challenges，Differentiation and Treatment Strategies of Traditional Chinese Medicine for Gastroesophageal Reflux Disease

VernacularTitle:胃食管反流病中医药研究现状、难点及辨治策略
Author: Fengyun WANG ¹ ; Mi LYU ¹ ; Bingduo ZHOU ² ; Beihua ZHANG ¹ ; Yi WANG ² ; Tingting XU ² ; Cong HE ² ; Xiaokang WANG ¹ ; Xin LIU ³ ; Yang WANG ³ ; Kaiyue HUANG ¹ ; Lusi XU ¹ ; Xudong TANG ⁴
Author Information

1. Xiyuan Hospital， China Academy of Chinese Medical Sciences，Beijing，100091
2. Yueyang Hospital of Integrated Traditional Chinese and Western Medicine，Shanghai University of Traditional Chinese Medicine
3. Beijing University of Chinese Medicine
4. Institute of Spleen and Stomach Diseases，Xiyuan Hospital，China Academy of Chinese Medical Sciences
Publication Type:Journal Article
Keywords: gastroesophageal reflux disease; traditional Chinese medicine therapy; integrated traditional Chinese and western medicine therapy; disease-syndrome combination
From: Journal of Traditional Chinese Medicine 2026;67(4):392-396
CountryChina
Language:Chinese
Abstract: This article systematically reviews the current research status as well as diagnosis and treatment strategies of traditional Chinese medicine （TCM） for gastroesophageal reflux disease （GERD）. Studies demonstrate that TCM， based on the "disease-syndrome combination" approach， exhibits multi-target advantages in alleviating symptoms of various GERD subtypes， promoting mucosal repair， regulating emotions， and facilitating the reduction of western medication. To address clinical challenges such as symptom overlap and limited therapeutic efficacy， strategies have been proposed including "treating different diseases with the same method" and integrated regulation based on viscera correlation. Future efforts should focus on elucidating the mechanisms of compound prescriptions， promoting TCM drug development under the "three-combination" evaluation framework that integrates TCM theory， human experience and clinical trial evidence， and optimizing integrated traditional and western medicine models to enhance GERD management.