DING Ying's Clinical Experience in Treating Systemic Lupus Erythematosus Based on Differentiation of Yin Fire，Latent Fire，and Fire Toxin
10.13288/j.11-2166/r.2026.04.004
- VernacularTitle:丁樱从阴火、伏火、火毒辨治系统性红斑狼疮经验
- Author:
Hongji WU
1
;
Min GAO
1
;
Yan XU
1
;
Xuejun LI
1
;
Jiexin SU
1
;
1
Author Information
1. Pediatric Hospital，The First Affiliated Hospital of Henan University of Chinese Medicine，Zhengzhou，450003
- Publication Type:Journal Article
- Keywords:
systemic lupus erythematosus;
yin fire;
latent fire;
fire toxin;
experience of famous doctors;
DING Ying
- From:
Journal of Traditional Chinese Medicine
2026;67(4):365-369
- CountryChina
- Language:Chinese
-
Abstract:
This paper summarizes Professor DING Ying's clinical experience in the treatment of systemic lupus erythematosus （SLE） through differentiation of three states， yin fire， latent fire， and fire toxin. It is proposed that fire pathogenic factors constitute a key pathological element running throughout the entire disease course of SLE. The evolution of its pathogenesis centers on these three states， spleen-kidney deficiency with the initial emergence of yin fire as the onset of disease， damage to yin by medicinal toxicity with internal blazing of latent fire as the driver of disease progression， and the interlocking of blood stasis and heat with intense scorching by fire toxin as the critical factor leading to severe and life-threatening conditions. Corresponding to these three stages， targeted prescriptions are formulated， Jiuwei Yishen Formulation （九味益肾方） to tonify the spleen and kidney， raise yang， and disperse fire； Ziyin Xiehuo Decoction （滋阴泄火汤） to nourish yin and fluids while clearing latent fire； and Santeng Changluo Jiedu Decoction （三藤畅络解毒汤） to dispel blood stasis， unblock the collaterals， detoxify， and restrain fire. This staged and integrated therapeutic strategy aims to address both root and branch and to achieve overall regulation， providing valuable guidance for the clinical differentiation and treatment of SLE.
