Application of extended antigen matching in transfusion for patients with autoimmune hemolytic anemia
10.13303/j.cjbt.issn.1004-549x.2026.01.016
- VernacularTitle:抗原拓展匹配在自身免疫性溶血性贫血输血中的应用
- Author:
Jinmu ZHUANG
1
;
Wenqing HUANG
1
;
Yuncong ZHANG
1
;
Shiqiao ZHOU
1
Author Information
1. Department of Transfusion Medicine, Shenzhen Hospital, Southern Medical University, Shenzhen 518110, China
- Publication Type:Journal Article
- Keywords:
blood group antigens;
extended matching;
autoimmune hemolytic anemia;
transfusion
- From:
Chinese Journal of Blood Transfusion
2026;39(1):109-113
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the clinical value of extended red blood cell (RBC) antigen matching in transfusion for patients with autoimmune hemolytic anemia (AIHA). Methods: Clinical transfusion procedures involving extended RBC antigen matching for cross-compatibility testing were analyzed in two AIHA cases. Results: Following the implementation of extended RBC antigen matching (four-tier matching), the major cross-match reaction results shifted from strongly positive to weakly positive. The hemoglobin (Hb) levels increased significantly after transfusion, with no observed hemolytic transfusion reactions (HTRs). Conclusion: Extended RBC antigen matching may provide a safe and effective transfusion strategy for AIHA patients.
