Development and evaluation of classification system for drug-related problems in China
- VernacularTitle:中国药物相关问题分类系统的构建及评价
- Author:
Shuang ZOU
1
;
Tingting LU
1
;
Lei BAO
1
;
Yun LIAO
2
;
Ling LI
1
;
Ping ZHANG
1
Author Information
1. Dept. of Pharmacy，Tongren Hospital，Shanghai Jiao Tong University School of Medicine，Shanghai 200336，China
2. Dept. of Clinical Pharmacy，Shanghai General Hospital，Shanghai Jiao Tong University School of Medicine，Shanghai 200080，China
- Publication Type:Journal Article
- Keywords:
classification system;
drug-related problem;
pharmaceutical care;
reliability;
applicability
- From:
China Pharmacy
2026;37(3):371-376
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To establish a Chinese drug-related problem （DRP） classification system applicable to pharmacist-led pharmaceutical care in China， providing pharmacists with an effective and practical tool for pharmaceutical care. METHODS A multi-stage process was employed to construct the DRP classification system， including literature review and analysis， comparison of existing classification systems， refinement of classification items and framework development， two rounds of standard case validation， expert discussion， and system revision. The Fleiss′ kappa test was used to calculate the consistency coefficient κ， assessing the reliability of pharmacists participating in evaluating the classification system. An electronic questionnaire comprising six items was employed to evaluate the system’s applicability. RESULTS The constructed Chinese DRP classification system comprised six sections [problem（including potential problems）， DRP evaluation， cause （including possible causes of potential problems）， intervention， acceptance of intervention and DRP status]， with 24 primary codes and 96 secondary codes. In the first round of case validation， κ values exceeded 0.4 for all sections except “intervention” and “DRP status”. In the second round， κ values exceeded 0.4 for all sections. In the applicability evaluation of the classification system， positive ratings （“strongly agree” or “agree”） exceeded 85% for all items. Specifically， positive ratings for“the classification system can provide appropriate category selection”，“ the classification system is comprehensive”，“ the classification system is convenient to use” and “the classification system is highly satisfactory” exceeded 92%. CONCLUSIONS The Chinese DRP classification system developed demonstrates both high reliability and applicability， providing an effective and practical classification tool for pharmacists in China to conduct pharmaceutical care.
