Discussion on Scientific Connotation of Vital Qi Strengthening for Detoxification Therapy in Treatment of Community-acquired Pneumonia Based on Theory of "Vital Qi Deficiency and Toxic Stasis"
10.13422/j.cnki.syfjx.20251796
- VernacularTitle:基于“正虚毒瘀”理论探讨扶正解毒法治疗社区获得性肺炎的科学内涵
- Author:
Hanxiao WANG
1
;
Zheyu LUAN
1
;
Haotian XU
1
;
Xin PENG
1
;
Ziming DANG
1
;
Kun YANG
1
;
Qianqian WANG
2
;
Jihong FENG
2
Author Information
1. Tianjin University of Traditional Chinese Medicine（TCM），Tianjin 301617，China
2. The Second Affiliated Hospital of Tianjin University of TCM，Tianjin 300250，China
- Publication Type:Journal Article
- Keywords:
community-acquired pneumonia;
vital Qi deficiency and toxic stasis;
vital Qi strengthening for detoxification;
theoretical discussion
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2026;32(4):226-234
- CountryChina
- Language:Chinese
-
Abstract:
Community-acquired pneumonia （CAP） refers to an infectious inflammation of the lung parenchyma （including the alveolar wall，that is，the broad pulmonary interstitium） acquired outside the hospital. Its common pathogens include streptococcus pneumoniae，respiratory viruses， mycoplasma pneumoniae， and so on. The related factors for the occurrence and development of CAP include patient characteristics （immune function，mucus production and clearance function，coagulation function，physical condition， and comorbidity） and pathogen characteristics （susceptibility，virulence，and antibiotic resistance）. The pathogenesis of CAP lies in immune deficiency，pathogen invasion，inflammatory response disorder，mucus production and clearance disorder， coagulation disorder， and so on. The pathogenesis of CAP in traditional Chinese medicine can be described as "vital Qi deficiency and toxic stasis". Vital Qi deficiency （lack of immunity） is the potential pathogenesis of the disease and easy to be invaded by external pathogens （respiratory pathogens）. Toxic stasis （inflammatory disorder，mucus production and clearance disorder，and coagulation dysfunction） is the key pathogenic factor. Vital Qi deficiency and toxic stasis are intermingled in a state of deficiency and excess，which suggests that the treatment of CAP lies in strengthening vital Qi and eliminating pathogenic factors. This involves strengthening vital Qi in the whole process to consolidate body resistance and nourish promordial Qi. It also involves clearing heat，eliminating phlegm，removing dampness，and dispelling stasis to dispel pathogenic toxins based on the syndrome differentiation. Its action mechanism is to regulate immune and inflammatory responses，resist pathogens，and improve mucus production and clearance， as well as coagulation disorders. Starting from the key pathogenesis of CAP，"vital Qi deficiency and toxic stasis"， this paper discussed the pathogenesis of CAP and summarized the action mechanism of vital Qi strengthening for detoxification in its treatment. It is intended to complement the theoretical system by identifying "vital Qi deficiency and toxic stasis" as the key pathogenesis underlying CAP and the scientific connotation of treating CAP with vital Qi strengthening for detoxification，thereby providing insights for its clinical application.
