Maternal oral-gut microbiome and artificial assisted reproduction
10.13591/j.cnki.kqyx.2025.01.001
- VernacularTitle:口腔-肠道微生物组与辅助生殖的研究进展
- Author:
Peiyue YANG
1
;
Xian PENG
;
Xuedong ZHOU
Author Information
1. 口腔疾病防治全国重点实验室,国家口腔医学中心,国家口腔疾病临床医学研究中心,四川大学华西口腔医院牙体牙髓病科,四川成都(610041)
- Keywords:
assisted reproductive technology;
oral-gut microbes;
in vitro fertilization;
translocation colonization
- From:
STOMATOLOGY
2025;45(1):1-7
- CountryChina
- Language:Chinese
-
Abstract:
Oral and intestinal microbiota are two of the most complex microbiota in the human body which play important roles in maintaining various physiological balances.Assisted reproductive technology(ART)is an in vitro treatment of gametes and embryos to help women conceive and produce healthy fetuses.Current assisted reproductive technology ART includes in vitro fertilization with or without oocyte intracytoplasmic sperm injection(IVF/ICSI).The ectopic colonization of oral-gut microbiota,their metabolites,and im-mune regulation mechanisms may affect the outcomes of assisted reproduction.This article mainly reviews the ways,mechanisms and potential beneficial interventions of oral and intestinal microbiota on women receiving artificial assisted reproductive therapy.