Regional and Ethnic-Specific Characteristics of the Gut Microbiome in China and Their Impact on Disease
10.12259/j.issn.2095-610X.S20251101
- VernacularTitle:中国地域性及民族特异性肠道微生物组特征及其对疾病的影响
- Author:
Binbin XIA
1
;
Rongxue HUANG
;
Hongju YANG
;
Yang SUN
Author Information
1. 昆明医科大学第一附属医院老年医学中心,老年消化科,云南 昆明 650032
- Keywords:
Gut microbiota;
Microbiota composition;
Ethnic minorities;
Regional variation
- From:
Journal of Kunming Medical University
2025;46(11):1-10
- CountryChina
- Language:Chinese
-
Abstract:
The composition of the Gut Microbiome(GM)is regulated by numerous factors,including geography,ethnicity,diet,and genetics.This review systematically synthesizes studies on the GM across different geographic regions and ethnic minority groups in China.It focuses on elucidating the impact of geographical factors and ethnic backgrounds on GM composition and structure and provides an in-depth discussion on the association between ethnicity-specific microbial taxa,their metabolic functions,and susceptibility to diseases.By systematically comparing microbial compositional differences in microbiota-related diseases among different populations,this review aims to uncover the underlying patterns.The findings are expected to provide a theoretical foundation for ethnicity-specific GM research,the elucidation of disease mechanisms,and the development of targeted prevention and control strategies.