Cardiac Protective Mechanism of Dexmedetomidine and Its Application in Clinic
10.12259/j.issn.2095-610X.S20250817
- VernacularTitle:右美托咪定的心脏保护作用机制及临床应用
- Author:
Jingjing ZHU
1
;
Xiaolei PEI
;
Hui WANG
;
Jinqiao QIAN
Author Information
1. 昆明市延安医院呈贡医院麻醉科,云南 昆明 650500
- Keywords:
Dexmedetomidine;
Cardioprotection;
Myocardial ischemia-reperfusion injury;
Programmed cell death;
Ferroptosis;
Pyroptosis
- From:
Journal of Kunming Medical University
2025;46(8):127-135
- CountryChina
- Language:Chinese
-
Abstract:
Cardiovascular disease remains a significant factor leading to patient mortality and influencing outcomes during the perioperative period.Dexmedetomidine is an α2-adrenergic receptor agonist with functions such as analgesia,sedation,and anti-anxiety.This review summarizes various types of findings regarding dexmedetomidine in myocardial ischemia/reperfusion injury and conducts in-depth discussions on the corresponding mechanisms of the results,aiming to further clarify the potential cardioprotective effects of dexmedetomidine in patients with heart diseases.
