The Clinical Features of Non-alcoholic Fatty Liver Disease and Its Risked Factors in Patients with Chronic Heart Failure
10.12259/j.issn.2095-610X.S20250809
- VernacularTitle:慢性心力衰竭合并NAFLD的临床特征及影响因素
- Author:
Rong SU
1
;
Ling LIN
;
Yuan ZHAO
;
Ailing YANG
;
Mingguo ZHANG
;
Hu ZHANG
;
Guoyu MA
Author Information
1. 昆明医科大学第一附属医院老年心脏内科,云南 昆明 650500
- Keywords:
Chronic heart failure;
Non-alcoholic fatty liver disease;
BMI;
Type 2 diabetes
- From:
Journal of Kunming Medical University
2025;46(8):65-71
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the prevalence and clinical features of nonalcoholic fatty liver disease(NAFLD)and its risk factors in patients with CHF,so as to provide the reference for early identification of NAFLD.Methods The data from 1120 CHF patients aged 14～89 was collected,including the general demographic information(age,gender,smoking status,height,weight,BMI,etc.),clinical diagnosis and treatment data(blood pressure,NYHA heart function classification,blood biochemical indicators,etc.),and medication use status.SPSS 27.0 was applied to analyze the clinical characteristics of CHF combined with NAFLD,and binary multivariate logistic regression was used to analyze the independent risk factors of CHF combined with NAFLD.Results Among the 1120 patients,634(56.6%)were male and 486(43.4%)were female.The prevalence of CHF patients with NAFLD was 25.0%.The results of univariate analysis showed that the weight of NAFLD patients BMI,systolic blood pressure,diastolic blood pressure,FPG,UA,left room expansion ratio,ALT,CHO,TG,obesity rate,hyperuricemia rate and β-blocker usage rate were all higher than those of non NAFLD patients.The age,BNP,HDL and ACEI/ARB/ARNI usage rate of NAFLD patients were lower than those of non NAFLD patients(all P<0.05).Logistic regression analysis showed that age(OR=0.988),FPG(OR=1.099),overweight(OR=3.497)and obesity(OR=9.193)were independent risk factors for CHF patients with NAFLD.Conclusion NAFLD may be a common complication in CHF patients,especially those who are young,have high FPG,overweight and obese.In the clinical practice,NAFLD screening,evaluation and management should be focused on CHF patients who are young,have high fasting blood sugar,overweight,and obese.
