Advances in the Study of Varenicline Combined with Nicotine Patches for the Treatment of Tobacco Dependence
10.12259/j.issn.2095-610X.S20250421
- VernacularTitle:伐尼克兰联合尼古丁贴剂治疗烟草依赖的研究进展
- Author:
Qiuqi WEI
1
;
Wenqian ZHAO
;
Ling LIU
Author Information
1. 昆明医科大学第一附属医院呼吸内科,云南 昆明 650032
- Keywords:
Varenicline;
Nicotine patch;
Tobacco dependence;
Combination therapy;
Efficacy
- From:
Journal of Kunming Medical University
2025;46(4):157-162
- CountryChina
- Language:Chinese
-
Abstract:
China has the highest number of smokers in the world with more than 1 million tobacco-related deaths each year.Smoking cessation is a feasible intervention to reduce the prevalence of smoking-related diseases and premature deaths.The smoking cessation therapies approved for use in China are ineffective for some tobacco dependent patients.In order to further improve the rate of smoking cessation,a combination of medications can be chosen,including varenicline combined with nicotine replacement therapy.However,there are conflicting evaluation conclusions on the effectiveness and safety of combination therapy.This article aims to review the mechanism of action,efficacy,and safety of varenicline combined with nicotine replacement therapy in the treatment of tobacco dependence,aiming to provide a basis for this combination therapy.
