Clinical Characteristics and Prognostic Analysis of Maintenance Hemodialysis Patients with Initial Treatment Tuberculosis
10.12259/j.issn.2095-610X.S20250417
- VernacularTitle:维持性血液透析合并初治结核患者临床特点及预后分析
- Author:
Haixia GU
1
;
Jiangli PENG
;
Anxin CHEN
;
Rui YIN
;
Qiqi XIAO
;
Jie CHEN
Author Information
1. 大理大学药学院,云南 大理 671000
- Keywords:
Tuberculosis;
Hemodialysis;
Chronic kidney disease;
Clinical features;
Treat;
Prognosis
- From:
Journal of Kunming Medical University
2025;46(4):129-135
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical characteristics,treatment and prognosis of patients undergoing the maintenance hemodialysis and treatment-naive tuberculosis and to explore the prognostic factors,so as to provide a reference for the clinical treatment of patients undergoing hemodialysis due to tuberculosis.Methods The clinical data of 70 patients undergoing hemodialysis with treatment-naive tuberculosis admitted to the Third People's Hospital of Kunming from October 31,2020～October 31,2023 were retrospectively collected,the clinical characteristics of the patients were analyzed,and the occurrence of adverse reactions,treatment outcomes and prognostic factors were observed.Results Among the 70 patients,pulmonary tuberculosis was the primary type(64 cases,accounting for 91.43％),and extrapulmonary tuberculosis was also quite common(56 cases,accounting for 80.00％).The most widely used anti-tuberculosis regimen was isoniazid,rifampicin,ethambutol,and moxifloxacin in a four-drug combination;During the anti-tuberculosis treatment,55 patients(78.57％)improved.A total of 13 adverse reactions occurred in 11 patients(15.71％),and the most common ones were itching,rash and blurred vision.The hemoglobin,lymphocyte count and CD8+T lymphocyte count in the treatment improvement group were higher than those in the ineffective group(P<0.05).Conclusion Dialysis patients have a high risk of tuberculosis infection,mainly pulmonary tuberculosis,and extrapulmonary tuberculosis is more common.78.57％of the patients hare improved after the tuberculosis treatment,but the overall prognosis is poor,and the low hemoglobin level is associated with ineffective treatment.
